Surgery for Combined Hamartoma of the Retina and Retinal Pigment Epithelium
There is no consensus on whether and when surgical treatment is indicated for combined hamartoma of the retina and retinal pigment epithelium (CHRRPE). We aim to discuss the benefits of surgical intervention and techniques that may improve the outcome. A 24-year-old man experienced progressive visual loss for 6 months in his left eye due to CHRRPE. At presentation, visual acuity was 1.3 LogMAR and fundoscopy revealed extensive tractional pre- and epiretinal membranes, subretinal exudation, and a vasoproliferative tumor in the inferior periphery. A complete vitrectomy was performed, while paying special attention to vitreous shaving at the vitreous base and removal of vitreoschisis-induced vitreous cortex remnants (VCR) from the retinal surface posterior to the vitreous base. Tractional membranes and internal limiting membrane were peeled, and the vasoproliferative tumor was excised. Silicone oil tamponade was removed 11 weeks after surgery. No intra- or postoperative complications occurred. Visual acuity improved to 0.8 LogMAR and remained stable for 48-month follow-up. Vitreoretinal surgery can prevent complications that occur with CHRRPE. In addition, visual function may improve even if the initial visual acuity is low. Timely and complete vitrectomy with extensive membranectomy and detection and removal of VCR is recommended to avoid complications in challenging CHRRPE.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Surgery for Combined Hamartoma of the Retina and Retinal Pigment Epithelium ; volume:12 ; number:3 ; year:2021 ; pages:778-783 ; extent:6
Case reports in ophthalmology ; 12, Heft 3 (2021), 778-783 (gesamt 6)
- Creator
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van der Sommen, Charlotte Maria
van Romunde, Saskia Helena Margaretha
van Overdam, Koen
- DOI
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10.1159/000518013
- URN
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urn:nbn:de:101:1-2022011223560876131593
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:37 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- van der Sommen, Charlotte Maria
- van Romunde, Saskia Helena Margaretha
- van Overdam, Koen
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The Retinome – Defining a reference transcriptome of the adult mammalian retina/retinal pigment epithelium
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Comparative 3D genome analysis between neural retina and retinal pigment epithelium reveals differential cis-regulatory interactions at retinal disease loci
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Retinal sensitivity and photoreceptor arrangement changes secondary to congenital simple hamartoma of retinal pigment epithelium
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Generation of Retinal Organoid-Retinal Pigment Epithelium Cocultures
Evaluation of focal damage in the retinal pigment epithelium layer in serous retinal pigment epithelium detachment
Congenital simple hamartoma of the retinal pigment epithelium with depigmentation at the margin in an Indian female
The Retinome – Defining a reference transcriptome of the adult mammalian retina/retinal pigment epithelium
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