Oxidative stress and antioxidants in health and disease
Abstract: The increase in the formation of reactive oxygen and reactive nitrogen species of endogenous or exogenous origin causes oxidative stress due to pro-oxidant and antioxidant imbalance that causes cellular damage in metabolism. This can increase inflammation of cells, apoptosis and necrosis, damage to DNA base damage, DNA and protein cross-links, lipid membrane peroxidation, and mitochondrial dysfunction. Antioxidants can be described as a system that protects biomolecules and the organism against the harmful effects of free radicals, reduces or repairs the damage done by reactive oxygen species (ROS) to the target molecule, and this is called antioxidant defense. It is known that the mechanisms caused by the increase in ROS resulting from oxidative stress are positively related to the pathology of many diseases such as cancer, metabolic syndrome, atherosclerosis, malaria, Alzheimer’s disease, rheumatoid arthritis, neurodegenerative diseases and preeclampsia.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
Oxidative stress and antioxidants in health and disease ; volume:47 ; number:1 ; year:2023 ; pages:1-11 ; extent:11
Journal of laboratory medicine ; 47, Heft 1 (2023), 1-11 (gesamt 11)
- Creator
-
Kıran, Tugba Raika
Otlu, Onder
Karabulut, Aysun Bay
- DOI
-
10.1515/labmed-2022-0108
- URN
-
urn:nbn:de:101:1-2023021713135350084467
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
14.08.2025, 10:57 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Kıran, Tugba Raika
- Otlu, Onder
- Karabulut, Aysun Bay
Other Objects (12)
Oxidative Stress, Plant-Derived Antioxidants and Liver Fibrosis
Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging
Oxidative stress and motorneuron disease
HCV, oxidative stress and liver disease
Effect of a walnut meal on postprandial oxidative stress and antioxidants in healthy individuals
The protective effects of antioxidants against endogenous and exogenous oxidative stress on bull sperm
Antioxidants reduce oxidative stress in follicular fluid of aged women undergoing IVF
Role of kindlin-1 during oxidative stress and effects of antioxidants on Kindler Syndrome keratinocytes
Oxidative stress and the use of antioxidants in diabetes: Linking basic science to clinical practice
Oxidative stress and ROS-mediated cellular events in RSV infection: potential protective roles of antioxidants
Oxidative stress : role in genomic damage and disease = Oxidativer Stress
Oxidative stress : role in genomic damage and disease = Oxidativer Stress
Oxidative Stress, Plant-Derived Antioxidants and Liver Fibrosis
Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging
Oxidative stress and motorneuron disease
HCV, oxidative stress and liver disease
Effect of a walnut meal on postprandial oxidative stress and antioxidants in healthy individuals
The protective effects of antioxidants against endogenous and exogenous oxidative stress on bull sperm
Antioxidants reduce oxidative stress in follicular fluid of aged women undergoing IVF
Role of kindlin-1 during oxidative stress and effects of antioxidants on Kindler Syndrome keratinocytes
Oxidative stress and the use of antioxidants in diabetes: Linking basic science to clinical practice
Oxidative stress and ROS-mediated cellular events in RSV infection: potential protective roles of antioxidants
Oxidative stress : role in genomic damage and disease = Oxidativer Stress
Oxidative stress : role in genomic damage and disease = Oxidativer Stress
Oxidative Stress, Plant-Derived Antioxidants and Liver Fibrosis
Reactive oxygen species, toxicity, oxidative stress, and antioxidants: chronic diseases and aging
Oxidative stress and motorneuron disease
HCV, oxidative stress and liver disease
Effect of a walnut meal on postprandial oxidative stress and antioxidants in healthy individuals
The protective effects of antioxidants against endogenous and exogenous oxidative stress on bull sperm
Antioxidants reduce oxidative stress in follicular fluid of aged women undergoing IVF
Role of kindlin-1 during oxidative stress and effects of antioxidants on Kindler Syndrome keratinocytes
Oxidative stress and the use of antioxidants in diabetes: Linking basic science to clinical practice
Oxidative stress and ROS-mediated cellular events in RSV infection: potential protective roles of antioxidants
Oxidative stress : role in genomic damage and disease = Oxidativer Stress