Long‐Lasting Simultaneous Epidermal and Dermal Microneedle‐Enabled Drug Delivery
Abstract: Different skin diseases, such as cancers, inflammatory conditions, and bacterial infections, manifest at distinct skin depths. Microneedle arrays, recognized for their painless and minimally invasive drug administration, can be customized to penetrate these layers simultaneously. Here, the design of the microneedles (MNs) in nonlinear ways with diverse needle heights on the array enabling concurrent drug delivery to various skin layers is engineered. Additionally, varying the base diameter of the needles in the array facilitates prolonged or intermittent drug release, depending on the biodegradation kinetics of these needles. MNs, microfabricated with a biocompatible and biodegradable polymer, are validated by skin administration. The nonlinear design of the MNs on the array introduces a novel perspective on addressing skin diseases at varying depths of the skin.
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Erschienen in
-
Long‐Lasting Simultaneous Epidermal and Dermal Microneedle‐Enabled Drug Delivery ; day:19 ; month:09 ; year:2024 ; extent:12
Advanced Materials Technologies ; (19.09.2024) (gesamt 12)
- Urheber
-
Sarabi, Misagh Rezapour
Farshi, Sara Soltanabadi
Saltik, Zeynep
Khosbakht, Saba
Buyukbabani, Nesimi
Agcaoglu, Orhan
Vural, Secil
Sitti, Metin
Tasoglu, Savas
- DOI
-
10.1002/admt.202400980
- URN
-
urn:nbn:de:101:1-2409191427020.559323158772
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
15.08.2025, 07:29 MESZ
Datenpartner
Dieses Objekt wird bereitgestellt von:
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Sarabi, Misagh Rezapour
- Farshi, Sara Soltanabadi
- Saltik, Zeynep
- Khosbakht, Saba
- Buyukbabani, Nesimi
- Agcaoglu, Orhan
- Vural, Secil
- Sitti, Metin
- Tasoglu, Savas
Ähnliche Objekte (12)
Remote Modular Electronics for Wireless Magnetic Devices
Pros and Cons: Magnetic versus Optical Microrobots
Self‐Sensing Paper Actuators Based on Graphite–Carbon Nanotube Hybrid Films
Magnetic Resonance Imaging‐Based Tracking and Navigation of Submillimeter‐Scale Wireless Magnetic Robots
Learning-based control and localization of magnetic soft millirobots
Avian‐Inspired Perching Mechanism for Jumping Robots
Development of a bioinspired multimodal mobile robot platform
Microrobotic Locomotion in Blood Vessels: A Computational Study on the Performance of Surface Microrollers in the Cardiovascular System
Microrobotic Locomotion in Blood Vessels: A Computational Study on the Performance of Surface Microrollers in the Cardiovascular System
3D-printed stimuli-responsive soft microrobots
Programmable Collective Behavior in Dynamically Self‐Assembled Mobile Microrobotic Swarms
Interfacial mechanics and liquid crystal structure of liquid gallium
Remote Modular Electronics for Wireless Magnetic Devices
Pros and Cons: Magnetic versus Optical Microrobots
Self‐Sensing Paper Actuators Based on Graphite–Carbon Nanotube Hybrid Films
Magnetic Resonance Imaging‐Based Tracking and Navigation of Submillimeter‐Scale Wireless Magnetic Robots
Learning-based control and localization of magnetic soft millirobots
Avian‐Inspired Perching Mechanism for Jumping Robots
Development of a bioinspired multimodal mobile robot platform
Microrobotic Locomotion in Blood Vessels: A Computational Study on the Performance of Surface Microrollers in the Cardiovascular System
Microrobotic Locomotion in Blood Vessels: A Computational Study on the Performance of Surface Microrollers in the Cardiovascular System
3D-printed stimuli-responsive soft microrobots
Programmable Collective Behavior in Dynamically Self‐Assembled Mobile Microrobotic Swarms
Interfacial mechanics and liquid crystal structure of liquid gallium
Remote Modular Electronics for Wireless Magnetic Devices
Pros and Cons: Magnetic versus Optical Microrobots
Self‐Sensing Paper Actuators Based on Graphite–Carbon Nanotube Hybrid Films
Magnetic Resonance Imaging‐Based Tracking and Navigation of Submillimeter‐Scale Wireless Magnetic Robots
Learning-based control and localization of magnetic soft millirobots
Avian‐Inspired Perching Mechanism for Jumping Robots
Development of a bioinspired multimodal mobile robot platform
Microrobotic Locomotion in Blood Vessels: A Computational Study on the Performance of Surface Microrollers in the Cardiovascular System
Microrobotic Locomotion in Blood Vessels: A Computational Study on the Performance of Surface Microrollers in the Cardiovascular System
3D-printed stimuli-responsive soft microrobots
Programmable Collective Behavior in Dynamically Self‐Assembled Mobile Microrobotic Swarms