Tubularization of the gastric pouch helps sustain weight loss after transoral outlet reduction for post-Roux-en-Y gastric bypass weight recurrence

Background Traditional transoral outlet reduction (TORe) is a minimally invasive endoscopic approach focused on reducing the aperture of the gastrojejunal (GJ) anastomosis, while the tubular transoral outlet reduction (tTORe) consists of tabularization of the distal pouch utilizing an O-shape gastroplasty suturing pattern. The primary aim of this study is to compare the short-term weight loss between TORe and tTORe. Methods Retrospective analysis of a prospectively maintained database was conducted at a tertiary care bariatric center of excellence. The study included patients with history of Roux-en-Y gastric bypass (RYGB) who had an endoscopic revision by TORe or tTORe and had follow-up data in their electronic medical record. The primary outcome was % total body weight loss (%TBWL). Results A total of 128 patients were included (tTORe=85, TORe=43). At 3 and 6 months, the tTORe and TORe cohorts presented similar %TBWL (3 months: 8.5 ±4.9 vs. 7.3 ±6.0, p=0.27 and 6 months: 8.1 ±7.4 vs. 6.8 ±5.6, p=0.44). At 9 months, there was a trend towards greater weight loss in the tTORe cohort (9.7 ± 8.6% vs. 5.1 ± 6.8%, p=0.053). At 12 months, the %TBWL was significantly higher in the tubularization group compared to the standard group (8.2 ±10.8 vs. 2.3 ±7.3%, p=0.01). Procedure time was significantly different between both groups (60.5 vs. 53.4 minutes, p=0.03). The adverse events rate was similar between groups (8.2% vs. 7.0% for tTORe and TORe, respectively, p=0.61). Conclusion The tTORe enhances efficacy and durability of the standard procedure without adding significant procedure-related risks.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Tubularization of the gastric pouch helps sustain weight loss after transoral outlet reduction for post-Roux-en-Y gastric bypass weight recurrence ; day:26 ; month:06 ; year:2023 ; Endoscopy International Open ; (26.06.2023)

Contributors, Places and Time

• Contributor: Abboud, Donna Maria ; Ghazi, Rabih ; Brunaldi, Vitor ; Gala, Khushboo ; Baroud, Serge ; Kerbage, Anthony ; AbdulRazzak, Farah ; Al Annan, Karim ; Rapaka, Babusai ; Yao, Rebecca ; Vargas, Eric J. ; Storm, Andrew C. ; Abu Dayyeh, Barham K.

Further information

• DOI: 10.1055/a-2117-8113
• URN: urn:nbn:de:101:1-2023081011034550531077
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 14.08.2025, 10:48 AM CEST