Adenomatoid odontogenic tumor expressing p53 and PCNA: A true benign neoplasm?
Abstract: Adenomatoid odontogenic tumor (AOT) is a relatively uncommon distinct odontogenic neoplasm. Histogenesis of AOT is still uncertain, and whether it represents anomalous hamartomatous growth or a true benign neoplasm is debatable. We report herein an unusual case of AOT occurring in the mandible. The tumor showed an unusual and aggressive clinical course, location, and radiographical and histopathological features expressing PCNA and p53 protein, which are suggestive of its proliferative potential, aggressive tumor behavior, and invasive characteristics. Based on these evidences, we suggested it to be a benign aggressive neoplasm rather than a hamartoma, though based on the analysis of single case it is still debatable.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Adenomatoid odontogenic tumor expressing p53 and PCNA: A true benign neoplasm? ; volume:2 ; number:03 ; year:2013 ; pages:328-331
European journal of general dentistry ; 2, Heft 03 (2013), 328-331
- Contributor
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Sah, Kunal
Kale, Alka D.
Kotrashetti, Vijaylaxmi
Chandra, Sunira
- DOI
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10.4103/2278-9626.116007
- URN
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urn:nbn:de:101:1-2021121611081110736482
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:25 AM CEST
Data provider
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Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Sah, Kunal
- Kale, Alka D.
- Kotrashetti, Vijaylaxmi
- Chandra, Sunira
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