Antiproliferative activity of lichen extracts on murine myeloma cells
Abstract: In the present study we report some preliminary results concerning the evaluation of antiproliferative activity on murine myeloma cells (P3X63-Ag8.653) of crude extracts of two common lichen species, Evernia prunastri and Xanthoria parietina. The results were evaluated by means of the MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] test, which is commonly used to assess the activity of living cells through mitochondrial dehydrogenases. They indicated that extracts of E. prunastri had no effect, while those of X. parietina significantly affected murine myeloma cell proliferation, with a reduction down to 75% for methanolic extracts. This opens perspectives for deeper investigations extended also to other mammalian cell lines.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Antiproliferative activity of lichen extracts on murine myeloma cells ; volume:64 ; number:1 ; year:2009 ; pages:59-62 ; extent:4
Biologia ; 64, Heft 1 (2009), 59-62 (gesamt 4)
- Urheber
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Triggiani, Doriana
Ceccarelli, Donatella
Tiezzi, Antonio
Pisani, Tommaso
Munzi, Silvana
Gaggi, Carlo
Loppi, Stefano
- DOI
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10.2478/s11756-009-0005-y
- URN
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urn:nbn:de:101:1-2409221600550.842790719013
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:21 MESZ
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Beteiligte
- Triggiani, Doriana
- Ceccarelli, Donatella
- Tiezzi, Antonio
- Pisani, Tommaso
- Munzi, Silvana
- Gaggi, Carlo
- Loppi, Stefano
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