Dual PI3K/mTOR inhibitor NVP-BEZ235 enhances radiosensitivity of head and neck squamous cell carcinoma (HNSCC) cell lines due to suppressed Double-Strand Break (DSB) repair by non-homologous end joining
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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In: Basel : MDPI
In: Cancers(12, 2020), H. 2
- Event
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Veröffentlichung
- (where)
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Jena
- (who)
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Friedrich-Schiller-Universität Jena
- (when)
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2020
- Event
-
Veröffentlichung
- (where)
-
Basel
- (who)
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MDPI
- (when)
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2020
- Creator
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Schötz, Ulrike
Balzer, Viola
Brandt, Friedrich-Wilhelm
Ziemann, Frank
Subtil, Florentine S.B.
Rieckmann, Thorsten
Köcher, Sabrina
Engenhart, Rita
Dikomey, Ekkehard
Wittig, Andrea
Arenz, Andrea
- DOI
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10.3390/cancers12020467
- URN
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urn:nbn:de:101:1-2020042902171790392115
- Rights
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Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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14.08.2025, 10:50 AM CEST
Data provider
This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Schötz, Ulrike
- Balzer, Viola
- Brandt, Friedrich-Wilhelm
- Ziemann, Frank
- Subtil, Florentine S.B.
- Rieckmann, Thorsten
- Köcher, Sabrina
- Engenhart, Rita
- Dikomey, Ekkehard
- Wittig, Andrea
- Arenz, Andrea
- Friedrich-Schiller-Universität Jena
- MDPI
Time of origin
- 2020
Other Objects (12)
NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitors, enhance tumor and endothelial cell radiosensitivity
Physical characterization of HNSCC cells
Impact of hypoxia on the double-strand break repair after photon and carbon ion irradiation of radioresistant HNSCC cells
Contributions of ionizing radiation-induced prompt DNA double-strand breaks to radiosensitivity of human cells of normal or tumor origin
Increased radiosensitivity and radiothermosensitivity of human pancreatic MIAPaCa-2 and U251 glioblastoma cell lines treated with the novel Hsp90 inhibitorNVP-HSP990
NU7441 Enhances the Radiosensitivity of Liver Cancer Cells
Increased radiosensitivity and radiothermosensitivity of human pancreatic MIA PaCa-2 and U251 glioblastoma cell lines treated with the novel Hsp90 inhibitor NVP-HSP990
GCN5 mediates DNA-PKcs crotonylation for DNA double-strand break repair and determining cancer radiosensitivity
Dual PI3K/mTOR Inhibitor NVP-BEZ235 Leads to a Synergistic Enhancement of Cisplatin and Radiation in Both HPV-Negative and -Positive HNSCC Cell Lines
Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity
Knockdown of PKM2 enhances radiosensitivity of cervical cancer cells
Role of GDF15 in radiosensitivity of breast cancer cells
NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitors, enhance tumor and endothelial cell radiosensitivity
Physical characterization of HNSCC cells
Impact of hypoxia on the double-strand break repair after photon and carbon ion irradiation of radioresistant HNSCC cells
Contributions of ionizing radiation-induced prompt DNA double-strand breaks to radiosensitivity of human cells of normal or tumor origin
Increased radiosensitivity and radiothermosensitivity of human pancreatic MIAPaCa-2 and U251 glioblastoma cell lines treated with the novel Hsp90 inhibitorNVP-HSP990
NU7441 Enhances the Radiosensitivity of Liver Cancer Cells
Increased radiosensitivity and radiothermosensitivity of human pancreatic MIA PaCa-2 and U251 glioblastoma cell lines treated with the novel Hsp90 inhibitor NVP-HSP990
GCN5 mediates DNA-PKcs crotonylation for DNA double-strand break repair and determining cancer radiosensitivity
Dual PI3K/mTOR Inhibitor NVP-BEZ235 Leads to a Synergistic Enhancement of Cisplatin and Radiation in Both HPV-Negative and -Positive HNSCC Cell Lines
Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity
Knockdown of PKM2 enhances radiosensitivity of cervical cancer cells
Role of GDF15 in radiosensitivity of breast cancer cells
NVP-BEZ235 and NVP-BGT226, dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitors, enhance tumor and endothelial cell radiosensitivity
Physical characterization of HNSCC cells
Impact of hypoxia on the double-strand break repair after photon and carbon ion irradiation of radioresistant HNSCC cells
Contributions of ionizing radiation-induced prompt DNA double-strand breaks to radiosensitivity of human cells of normal or tumor origin
Increased radiosensitivity and radiothermosensitivity of human pancreatic MIAPaCa-2 and U251 glioblastoma cell lines treated with the novel Hsp90 inhibitorNVP-HSP990
NU7441 Enhances the Radiosensitivity of Liver Cancer Cells
Increased radiosensitivity and radiothermosensitivity of human pancreatic MIA PaCa-2 and U251 glioblastoma cell lines treated with the novel Hsp90 inhibitor NVP-HSP990
GCN5 mediates DNA-PKcs crotonylation for DNA double-strand break repair and determining cancer radiosensitivity
Dual PI3K/mTOR Inhibitor NVP-BEZ235 Leads to a Synergistic Enhancement of Cisplatin and Radiation in Both HPV-Negative and -Positive HNSCC Cell Lines
Cellular plasticity upon proton irradiation determines tumor cell radiosensitivity
Knockdown of PKM2 enhances radiosensitivity of cervical cancer cells