Low‐Dose Bisphenol A Exposure: A Seemingly Instigating Carcinogenic Effect on Breast Cancer
Breast cancer is the fifth most common cause of cancer death in the world and the second most common fatal cancer in women. Epidemiological studies and clinical data have indicated that hormones, including estrogen, progesterone, and prolactin, play important roles in the initiation and progression of breast cancer. Bisphenol A (BPA) is one of the most commonly used and thoroughly studied endocrine disruptors. It can be released from consumer products and deposited in the environment, thus creating potential for human exposure through oral, inhaled, and dermal routes. Some recent reviews have summarized the known mechanisms of endocrine disruptions by BPA in human diseases, including obesity, reproductive disorders, and birth defects. However, large knowledge gaps still exist on the roles BPA may play in cancer initiation and development. Evidence from animal and in vitro studies has suggested an association between increased incidence of breast cancer and BPA exposure at doses below the safe reference doses that are the most environmentally relevant. Most current studies have paid little attention to the cancer‐promoting properties of BPA at low doses. In this review, recent findings on the carcinogenic effects of low‐dose BPA on breast cancer and discussed possible biologic mechanisms are summarized.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
Low‐Dose Bisphenol A Exposure: A Seemingly Instigating Carcinogenic Effect on Breast Cancer ; volume:4 ; number:2 ; year:2017 ; extent:14
Advanced science ; 4, Heft 2 (2017) (gesamt 14)
- Creator
-
Wang, Zhe
Liu, Huiyu
Liu, Sijin
- DOI
-
10.1002/advs.201600248
- URN
-
urn:nbn:de:101:1-2022091405492543171079
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
15.08.2025, 7:26 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Wang, Zhe
- Liu, Huiyu
- Liu, Sijin
Other Objects (12)
Coupled and Coordinated Development of Economic Growth and Green Sustainability in a Manufacturing Enterprise under the Context of Dual Carbon Goals: Carbon Peaking and Carbon Neutrality
De-novo Proteinstrukturmodellierung mit Hilfe von Dichtekarten
Prognostic and clinicopathological significance of long noncoding RNA CTD-2510F5.4 in gastric cancer
Metal‐Free Electrocatalysts for Oxygen Reduction to Hydrogen Peroxide
Terahertz and Infrared Spectroscopy on Low-Dimensional Quantum Magnets
A comparative study of urban ecological resilience in the Yangtze River Economic Belt and the Yellow River Basin
The Joint Effect of Mid-latitude Winds and the Westerly Quasi-Biennial Oscillation Phase on the Antarctic Stratospheric Polar Vortex and Ozone
Myeloid Neoplasm with PCM1-PDGFRB Transcript Responded to Low-Dose Imatinib: One Case Report with Literature Review
Microbial nitrogen cycling in sediments of an agricultural stream as impacted by stream-groundwater exchange
Range-azimuth decouple beamforming for frequency diverse array with Costas-sequence modulated frequency offsets
Effects of principal stress rotation on the wave–seabed interactions
The Link Between Math Anxiety and Math Achievement: The Role of Afterschool Learning
Coupled and Coordinated Development of Economic Growth and Green Sustainability in a Manufacturing Enterprise under the Context of Dual Carbon Goals: Carbon Peaking and Carbon Neutrality
De-novo Proteinstrukturmodellierung mit Hilfe von Dichtekarten
Prognostic and clinicopathological significance of long noncoding RNA CTD-2510F5.4 in gastric cancer
Metal‐Free Electrocatalysts for Oxygen Reduction to Hydrogen Peroxide
Terahertz and Infrared Spectroscopy on Low-Dimensional Quantum Magnets
A comparative study of urban ecological resilience in the Yangtze River Economic Belt and the Yellow River Basin
The Joint Effect of Mid-latitude Winds and the Westerly Quasi-Biennial Oscillation Phase on the Antarctic Stratospheric Polar Vortex and Ozone
Myeloid Neoplasm with PCM1-PDGFRB Transcript Responded to Low-Dose Imatinib: One Case Report with Literature Review
Microbial nitrogen cycling in sediments of an agricultural stream as impacted by stream-groundwater exchange
Range-azimuth decouple beamforming for frequency diverse array with Costas-sequence modulated frequency offsets
Effects of principal stress rotation on the wave–seabed interactions
The Link Between Math Anxiety and Math Achievement: The Role of Afterschool Learning
Coupled and Coordinated Development of Economic Growth and Green Sustainability in a Manufacturing Enterprise under the Context of Dual Carbon Goals: Carbon Peaking and Carbon Neutrality
De-novo Proteinstrukturmodellierung mit Hilfe von Dichtekarten
Prognostic and clinicopathological significance of long noncoding RNA CTD-2510F5.4 in gastric cancer
Metal‐Free Electrocatalysts for Oxygen Reduction to Hydrogen Peroxide
Terahertz and Infrared Spectroscopy on Low-Dimensional Quantum Magnets
A comparative study of urban ecological resilience in the Yangtze River Economic Belt and the Yellow River Basin
The Joint Effect of Mid-latitude Winds and the Westerly Quasi-Biennial Oscillation Phase on the Antarctic Stratospheric Polar Vortex and Ozone
Myeloid Neoplasm with PCM1-PDGFRB Transcript Responded to Low-Dose Imatinib: One Case Report with Literature Review
Microbial nitrogen cycling in sediments of an agricultural stream as impacted by stream-groundwater exchange
Range-azimuth decouple beamforming for frequency diverse array with Costas-sequence modulated frequency offsets
Effects of principal stress rotation on the wave–seabed interactions