Iodination of industrially important aromatic compounds using N-iodosuccinimide by grinding method

Abstract: Iodination of various industrially and pharmaceutically important substituted aromatics has been achieved using N-iodosuccinimide (NIS) in solid state by grinding at room temperature. This method provides several advantages such as short reaction time (5–8 min), high yields (94–99%), and nonhazardous and simple work-up procedure. High gas chromatography (GC) purity (95–99.9%) suggests that the reaction is highly selective. Substrates which are sensitive to oxidation, viz aniline and phenols are iodinated smoothly in high yield.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Iodination of industrially important aromatic compounds using N-iodosuccinimide by grinding method ; volume:7 ; number:6 ; year:2018 ; pages:477-486 ; extent:10
Green processing & synthesis ; 7, Heft 6 (2018), 477-486 (gesamt 10)

Creator
Sharma, Vivek
Srivastava, Priyanka
Bhardwaj, Santosh Kumar
Agarwal, D.D.

DOI
10.1515/gps-2017-0072
URN
urn:nbn:de:101:1-2501120357161.623551354376
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:34 AM CEST

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Associated

  • Sharma, Vivek
  • Srivastava, Priyanka
  • Bhardwaj, Santosh Kumar
  • Agarwal, D.D.

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