HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 1432-0533

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS ; volume:144 ; number:3 ; day:27 ; month:7 ; year:2022 ; pages:465-488 ; date:9.2022
Acta neuropathologica ; 144, Heft 3 (27.7.2022), 465-488, 9.2022

Creator: Braems, Elke
Bercier, Valérie
Van Schoor, Evelien
Heeren, Kara
Beckers, Jimmy
Fumagalli, Laura
Dedeene, Lieselot
Moisse, Matthieu
Geudens, Ilse
Hersmus, Nicole
Mehta, Arpan R.
Selvaraj, Bhuvaneish T.
Chandran, Siddharthan
Ho, Ritchie
Thal, Dietmar
Van Damme, Philip
Swinnen, Bart
Van Den Bosch, Ludo

Contributor: SpringerLink (Online service)

DOI: 10.1007/s00401-022-02471-y

URN: urn:nbn:de:101:1-2022110320590746257751

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:35 AM CEST

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Associated

Braems, Elke
Bercier, Valérie
Van Schoor, Evelien
Heeren, Kara
Beckers, Jimmy
Fumagalli, Laura
Dedeene, Lieselot
Moisse, Matthieu
Geudens, Ilse
Hersmus, Nicole
Mehta, Arpan R.
Selvaraj, Bhuvaneish T.
Chandran, Siddharthan
Ho, Ritchie
Thal, Dietmar
Van Damme, Philip
Swinnen, Bart
Van Den Bosch, Ludo
SpringerLink (Online service)

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Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders

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GSTM2 alleviates heart failure by inhibiting DNA damage in cardiomyocytes

Repeat length of C9orf72-associated glycine–alanine polypeptides affects their toxicity

A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism

Enhancing mitochondrial proteolysis alleviates alpha-synuclein-mediated cellular toxicity

Dexamethasone Alleviates Tumor-Associated Brain Damage and Angiogenesis

Poly-glycine–alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3

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Reduction in mitochondrial iron alleviates cardiac damage during injury

Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration

Investigating the spread and toxicity of glycine-alanine dipeptides in C9orf72 ALS/FTD using Drosophila melanogaster

Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders

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GSTM2 alleviates heart failure by inhibiting DNA damage in cardiomyocytes

Repeat length of C9orf72-associated glycine–alanine polypeptides affects their toxicity

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Enhancing mitochondrial proteolysis alleviates alpha-synuclein-mediated cellular toxicity

Dexamethasone Alleviates Tumor-Associated Brain Damage and Angiogenesis

Poly-glycine–alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3

CST3 alleviates bilirubin-induced neurocytes’ damage by promoting autophagy

Reduction in mitochondrial iron alleviates cardiac damage during injury

Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration

Investigating the spread and toxicity of glycine-alanine dipeptides in C9orf72 ALS/FTD using Drosophila melanogaster

Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders

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HNRNPK alleviates RNA toxicity by counteracting DNA damage in C9orf72 ALS

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Other Objects (12)

RNA versus protein toxicity in C9orf72 ALS/FTLD

GSTM2 alleviates heart failure by inhibiting DNA damage in cardiomyocytes

Repeat length of C9orf72-associated glycine–alanine polypeptides affects their toxicity

A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism

Enhancing mitochondrial proteolysis alleviates alpha-synuclein-mediated cellular toxicity

Dexamethasone Alleviates Tumor-Associated Brain Damage and Angiogenesis

Poly-glycine–alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3

CST3 alleviates bilirubin-induced neurocytes’ damage by promoting autophagy

Reduction in mitochondrial iron alleviates cardiac damage during injury

Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration

Investigating the spread and toxicity of glycine-alanine dipeptides in C9orf72 ALS/FTD using Drosophila melanogaster

Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders

RNA versus protein toxicity in C9orf72 ALS/FTLD

GSTM2 alleviates heart failure by inhibiting DNA damage in cardiomyocytes

Repeat length of C9orf72-associated glycine–alanine polypeptides affects their toxicity

A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism

Enhancing mitochondrial proteolysis alleviates alpha-synuclein-mediated cellular toxicity

Dexamethasone Alleviates Tumor-Associated Brain Damage and Angiogenesis

Poly-glycine–alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3

CST3 alleviates bilirubin-induced neurocytes’ damage by promoting autophagy

Reduction in mitochondrial iron alleviates cardiac damage during injury

Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration

Investigating the spread and toxicity of glycine-alanine dipeptides in C9orf72 ALS/FTD using Drosophila melanogaster

Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders

RNA versus protein toxicity in C9orf72 ALS/FTLD

GSTM2 alleviates heart failure by inhibiting DNA damage in cardiomyocytes

Repeat length of C9orf72-associated glycine–alanine polypeptides affects their toxicity

A zebrafish model for C9orf72 ALS reveals RNA toxicity as a pathogenic mechanism

Enhancing mitochondrial proteolysis alleviates alpha-synuclein-mediated cellular toxicity

Dexamethasone Alleviates Tumor-Associated Brain Damage and Angiogenesis

Poly-glycine–alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3

CST3 alleviates bilirubin-induced neurocytes’ damage by promoting autophagy

Reduction in mitochondrial iron alleviates cardiac damage during injury

Glycine-alanine dipeptide repeat protein contributes to toxicity in a zebrafish model of C9orf72 associated neurodegeneration

Investigating the spread and toxicity of glycine-alanine dipeptides in C9orf72 ALS/FTD using Drosophila melanogaster

Reduced autophagy upon C9ORF72 loss synergizes with dipeptide repeat protein toxicity in G4C2 repeat expansion disorders

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