Arbeitspapier
Estimation of genetic parameters using molecular markers and EM-algorithms
In this paper we present a new method for estimating genetic parameters of an F2- generation model. Using an iterative algorithm we derive explicit expressions for the Maximum Likelihood estimates of the additive and dominance effects. Finally we calculate the variance covariance matrix of our Maximum Likelihood estimates, which enables us to determine a confidence interval for the location of a quantitative trait locus.
- Language
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Englisch
- Bibliographic citation
-
Series: Technical Report ; No. 1999,48
- Subject
-
molecular genetics
Maximum Likelihood estimation
EM and ECM algorithms
variance-and covariance matrix of Maximum Likelihood estimates
confidence intervals for genetic parameters
- Event
-
Geistige Schöpfung
- (who)
-
Emrich, Katharina
Wolfgang, Urfer
- Event
-
Veröffentlichung
- (who)
-
Universität Dortmund, Sonderforschungsbereich 475 - Komplexitätsreduktion in Multivariaten Datenstrukturen
- (where)
-
Dortmund
- (when)
-
1999
- Handle
- Last update
-
10.03.2025, 11:44 AM CET
Data provider
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ZBW - Deutsche Zentralbibliothek für Wirtschaftswissenschaften - Leibniz-Informationszentrum Wirtschaft. If you have any questions about the object, please contact the data provider.
Object type
- Arbeitspapier
Associated
- Emrich, Katharina
- Wolfgang, Urfer
- Universität Dortmund, Sonderforschungsbereich 475 - Komplexitätsreduktion in Multivariaten Datenstrukturen
Time of origin
- 1999
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