Cystoid Macular Edema following Treatment with Nanoparticle Albumin-Bound Paclitaxel and Atezolizumab for Metastatic Breast Cancer

Cystoid macular edema (CME) is a rare side effect associated with chemotherapy. Although the development of CME has been reported to occur following treatment with taxane drugs, such as nanoparticle albumin-bound paclitaxel (Nab-PTX), the occurrence of CME with treatment with atezolizumab has not yet been reported. Here, we report the case of a 49-year-old woman who developed CME 19 months into chemotherapy with Nab-PTX and atezolizumab. Improvement was not achieved with steroid injections into the Tenon’s sac, and Nab-PTX and atezolizumab treatments were ceased. One month later, there was subjective improvement in her symptoms. Although many reports have indicated that cessation of chemotherapy has successfully improved CME, a specific treatment for CME has not yet been established. Clinicians should be aware of the ophthalmologic side effects and offer immediate treatment if symptoms develop.

Standort
Deutsche Nationalbibliothek Frankfurt am Main
Umfang
Online-Ressource
Sprache
Englisch

Erschienen in
Cystoid Macular Edema following Treatment with Nanoparticle Albumin-Bound Paclitaxel and Atezolizumab for Metastatic Breast Cancer ; volume:16 ; number:1 ; year:2023 ; pages:1121-1128 ; extent:8
Case reports in oncology ; 16, Heft 1 (2023), 1121-1128 (gesamt 8)

Urheber
Yamane, Hiroaki
Itagaki, Tomoko
Kajitani, Keiko
Koura, Yuji
Kawabuchi, Yoshiharu
Ohara, Masahiro

DOI
10.1159/000533999
URN
urn:nbn:de:101:1-2023122800001993417086
Rechteinformation
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Letzte Aktualisierung
15.08.2025, 07:26 MESZ

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Beteiligte

  • Yamane, Hiroaki
  • Itagaki, Tomoko
  • Kajitani, Keiko
  • Koura, Yuji
  • Kawabuchi, Yoshiharu
  • Ohara, Masahiro

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