Magnetomotive Displacement of Magnetic Nanoparticles in Different Tissue Phantoms
Abstract: Magnetic nanoparticles (MNPs) can be used in various biomedical applications, such as magnetic drug targeting (MDT) or magnetic hyperthermia for cancer treatment. MNPs are injected into the body and accumulated with an external magnetic field at the tumor site. For therapy monitoring, the MNPs distribution has to be accurately mapped in real time. Magnetomotive ultrasound (MMUS) is a suitable technique for this purpose. It was already demonstrated that MMUS can map the accumulation process of MNPs during MDT. Moreover, inverse MMUS is an advanced technique to quantify MNP distribution. This method simulates the displacement of MNPs and surrounding tissues and compares the results to measured data. Understanding how magnetomotive displacement behaves in various elastic environments is crucial for advancing inverse MMUS and accurately quantifying MNP distributions. In this study, ultrasound tissue phantoms were fabricated with varying elastic parameters, incorporating MNPs. Subsequently, their MMUS displacement is assessed.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Magnetomotive Displacement of Magnetic Nanoparticles in Different Tissue Phantoms ; volume:10 ; number:4 ; year:2024 ; pages:324-327 ; extent:4
Current directions in biomedical engineering ; 10, Heft 4 (2024), 324-327 (gesamt 4)
- Creator
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Huber, Christian Marinus
Heim, Christian
Li, Jiaqi
Ermert, Helmut
Rupitsch, Stefan J.
Ullmann, Ingrid
Lyer, Stefan
- DOI
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10.1515/cdbme-2024-2079
- URN
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urn:nbn:de:101:1-2412181739220.223924289090
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:28 AM CEST
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Associated
- Huber, Christian Marinus
- Heim, Christian
- Li, Jiaqi
- Ermert, Helmut
- Rupitsch, Stefan J.
- Ullmann, Ingrid
- Lyer, Stefan
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