Structures and mechanism of the monoamine oxidase family
Abstract: Members of the monoamine oxidase family of flavoproteins catalyze the oxidation of primary and secondary amines, polyamines, amino acids, and methylated lysine side chains in proteins. The enzymes have similar overall structures, with conserved flavin adenine dinucleotide (FAD)-binding domains and varied substrate-binding sites. Multiple mechanisms have been proposed for the catalytic reactions of these enzymes. The present review compares the structures of different members of the family and the various mechanistic proposals.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
Structures and mechanism of the monoamine oxidase family ; volume:2 ; number:5 ; year:2011 ; pages:365-377
Biomolecular concepts ; 2, Heft 5 (2011), 365-377
- Creator
-
Gaweska, Helena
Fitzpatrick, Paul F.
- DOI
-
10.1515/BMC.2011.030
- URN
-
urn:nbn:de:101:1-2409241607214.281937180782
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
15.08.2025, 7:25 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Gaweska, Helena
- Fitzpatrick, Paul F.