Lipomas as an Extremely Rare Cause for Brachial Plexus Compression: A Case Series and Systematic Review

Abstract: Introduction Brachial plexus lipomas are extremely rare benign tumors that may cause slow progression of neurological deficits leading to thoracic outlet syndrome. Up to now, surgery remains challenging. The aim of this study is to present our surgical treatment regime and long-term neurological outcome in three cases of giant brachial plexus lipomas and to show results of systematic review. Patients and Methods Retrospective analysis of our database “peripheral nerve lesion” to identify patients suffering from brachial plexus lipomas between January 1, 2012, and December 31, 2019. Systematic review was performed for literature published until March 31, 2020, analyzing PubMed, Google Scholar, Scopus, and the Cochrane Collaboration Library independently by two authors. Results Over the past years, three patients suffering from giant brachial plexus lipomas attended to our neurosurgical department. All patients underwent preoperative magnetic resonance imaging (MRI), ultrasound examinations, and electrophysiological testing. Tumors were removed microsurgically via anterior/posterior, supraclavicular/infraclavicular, and combined approaches. The patients were accessed postoperatively by MRI and clinical follow-up. Systematic review of the literature revealed 22 cases, which were analyzed in regard to demographics, surgical treatment, and neurological outcome. Conclusion Brachial plexus lipomas are an extremely rare cause for brachial plexus compression. Total microsurgical removal with intraoperative electrophysiological monitoring is the treatment of choice with excellent long-term MRI and clinical outcome.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Lipomas as an Extremely Rare Cause for Brachial Plexus Compression: A Case Series and Systematic Review ; volume:16 ; number:01 ; year:2021 ; pages:e10-e16 ; Journal of brachial plexus and peripheral nerve injury ; 16, Heft 01 (2021), e10-e16

Contributors, Places and Time

• Contributor: Gembruch, Oliver ; Ahmadipour, Yahya ; Chihi, Mehdi ; Dinger, Thiemo F. ; Rauschenbach, Laurèl ; Pierscianek, Daniela ; Jabbarli, Ramazan ; Sure, Ulrich ; Wrede, Karsten Henning ; Uerschels, Anne-Kathrin

Further information

• DOI: 10.1055/s-0041-1726087
• URN: urn:nbn:de:101:1-2022030612053814176694
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:25 AM CEST