Bacterial Membrane Vesicles: Physiological Roles, Infection Immunology, and Applications

Abstract: Bacterial or fungal membrane vesicles, traditionally considered as microbial metabolic wastes, are secreted mainly from the outer membrane or cell membrane of microorganisms. However, recent studies have shown that these vesicles play essential roles in direct or indirect communications among microorganisms and between microorganisms and hosts. This review aims to provide an updated understanding of the physiological functions and emerging applications of bacterial membrane vesicles, with a focus on their biogenesis, mechanisms of adsorption and invasion into host cells, immune stimulatory effects, and roles in the much‐concerned problem of bacterial resistance. Additionally, the potential applications of these vesicles as biomarkers, vaccine candidates, and drug delivery platforms are discussed.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Bacterial Membrane Vesicles: Physiological Roles, Infection Immunology, and Applications ; day:25 ; month:06 ; year:2023 ; extent:23
Advanced science ; (25.06.2023) (gesamt 23)

Creator
Gan, Yixiao
Zhao, Gang
Wang, Zhicheng
Zhang, Xingcai
Wu, Mei X.
Lu, Min

DOI
10.1002/advs.202301357
URN
urn:nbn:de:101:1-2023062615083042938450
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
14.08.2025, 10:47 AM CEST

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Associated

  • Gan, Yixiao
  • Zhao, Gang
  • Wang, Zhicheng
  • Zhang, Xingcai
  • Wu, Mei X.
  • Lu, Min

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