Balloon Aortic Valvuloplasty with or without Percutaneous Coronary Intervention in the Transcatheter Aortic Valve Replacement Era

Abstract: Introduction: The role of balloon aortic valvuloplasty (BAV) in the era of transcatheter aortic valve replacement remains a topic of debate. We sought to study the safety and feasibility of combined BAV and percutaneous coronary intervention (BAV-PCI). Methods: Between November 2009 and July 2020, all patients undergoing BAV were identified and divided into three groups: combined BAV-PCI (group A), BAV with significant unrevascularised CAD (group B), and BAV without significant CAD (group C). Procedural outcomes and 30-day and one-year mortality were compared. Results: A total of 264 patients were studied (n = 84, 93, and 87 patients in groups A, B, and C, respectively). The STS score was 10.2 ± 8, 13.3 ± 19, and 8.1 ± 7, p = 0.026, in groups A, B, and C, respectively. VARC-3 adjudicated complications were similar among groups (11%, 13%, and 5%, respectively, p = 0.168, respectively). Thirty-day and one-year mortality were 9.8% (n = 26) and 32% (n = 86) of the entire cohort. The differences among groups did not reach statistical significance. Using univariate Cox regression analysis, group B patients were at higher risk of dying compared to group A patients (HR 1.58, 95% CI: 1.11–2.25, p = 0.010). With multivariate Cox regression analysis, the predictors of mortality were STS score, cardiogenic shock, mode of presentation, and lack of subsequent definitive valve intervention. Conclusion: In high-risk patients with aortic valve stenosis, combined BAV-PCI is safe and feasible with comparable outcomes to BAV with and without significant CAD.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Balloon Aortic Valvuloplasty with or without Percutaneous Coronary Intervention in the Transcatheter Aortic Valve Replacement Era ; volume:149 ; number:5 ; year:2024 ; pages:487-494 ; extent:8
Cardiology ; 149, Heft 5 (2024), 487-494 (gesamt 8)

Creator
Aldalati, Omar
Jackson, Matthew
Vijayan, Seth
Telyuk, Pyotr
Hayat, Umair
Bashir, Shaza
Vahabi, Sharareh
McCalmont, Gemma
de Belder, Mark A.
Muir, Douglas
Williams, Paul D.

DOI
10.1159/000538521
URN
urn:nbn:de:101:1-2410100026489.057847153413
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:35 AM CEST

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Associated

  • Aldalati, Omar
  • Jackson, Matthew
  • Vijayan, Seth
  • Telyuk, Pyotr
  • Hayat, Umair
  • Bashir, Shaza
  • Vahabi, Sharareh
  • McCalmont, Gemma
  • de Belder, Mark A.
  • Muir, Douglas
  • Williams, Paul D.

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