Towards clinically relevant oculomotor biomarkers in early schizophrenia

Abstract: In recent years, psychiatric research has focused on the evaluation and implementation of biomarkers in the clinical praxis. Oculomotor function deviances are among the most consistent and replicable cognitive deficits in schizophrenia and have been suggested as viable candidates for biomarkers. In this narrative review, we focus on oculomotor function in first-episode psychosis, recent onset schizophrenia as well as individuals at high risk for developing psychosis. We critically discuss the evidence for the possible utilization of oculomotor function measures as diagnostic, susceptibility, predictive, monitoring, and prognostic biomarkers for these conditions. Based on the current state of research we conclude that there are not sufficient data to unequivocally support the use of oculomotor function measures as biomarkers in schizophrenia.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch
Notes
Frontiers in behavioral neuroscience. - 15 (2021) , 688683, ISSN: 1662-5153

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2021
Creator
Athanasopoulos, Fotios
Saprikis, Orionas-Vasilis
Margeli, Myrto
Klein, Christoph
Smyrnis, Nikolaos

DOI
10.3389/fnbeh.2021.688683
URN
urn:nbn:de:bsz:25-freidok-2192399
Rights
Kein Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
14.08.2025, 10:57 AM CEST

Data provider

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Associated

  • Athanasopoulos, Fotios
  • Saprikis, Orionas-Vasilis
  • Margeli, Myrto
  • Klein, Christoph
  • Smyrnis, Nikolaos
  • Universität

Time of origin

  • 2021

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