PAMAM dendrimers — diverse biomedical applications. Facts and unresolved questions

Abstract: In this mini-review a number of novel outcomes, originating from studies in the field of PAMAM dendrimers, are presented and discussed. Owing to the multi-disciplinary nature of dendrimer chemistry it seems important to focus on the relevant topical research of PAMAM dendrimers, including their function, toxicity, surface modifications, and also possible new applications of these spherical polymers. We also consider the possibilities of specific functionalisation of PAMAM dendrimers — both novel ideas and those that have already been reported; as well as their cell-mediated effects (toxic and non-toxic). Then the reactivity of dendrimers’ terminal groups, and their anticipated protective role against modifications of biomacromolecules, are discussed with regard to future developments in biomedical research.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
PAMAM dendrimers — diverse biomedical applications. Facts and unresolved questions ; volume:4 ; number:4 ; year:2009 ; pages:434-451 ; extent:18
Open life sciences ; 4, Heft 4 (2009), 434-451 (gesamt 18)

Creator
Labieniec, Magdalena
Watala, Cezary

DOI
10.2478/s11535-009-0056-7
URN
urn:nbn:de:101:1-2409201835190.239838042649
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:38 AM CEST

Data provider

This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.

Associated

  • Labieniec, Magdalena
  • Watala, Cezary

Other Objects (12)