The paths to the atomic structures of proteins and nucleic acids

Abstract: Atomic structures of large biological molecules were first established by scattering X-rays in protein crystals and later with crystals of nucleic acids. Good crystals allow for an accuracy of 0.1 Å (10−11 m) that may reveal details of catalytic processes. The novel cryo-electron microscopy method does not need crystals and it can establish chain folds confidently. Chain folds can also be derived from NMR data to produce numerous binary atomic distances. Recently, chain folds for a given amino acid sequence were derived by mere computing, based on the presently available large library of proteins that are related by their amino acid

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch
Notes
ISSN: 2199-3793

Classification
Biowissenschaften, Biologie

Event
Veröffentlichung
(where)
Freiburg
(who)
Universität
(when)
2023
Creator

DOI
10.1007/s40828-023-00180-x
URN
urn:nbn:de:bsz:25-freidok-2372667
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
14.08.2025, 11:04 AM CEST

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Associated

Time of origin

  • 2023

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