Double (3 + 2) cycloadditions for diastereoselective synthesis of spirooxindole pyrrolizidines
Abstract: One-pot two sequential [3 + 2] cycloadditions of azomethine ylides with different dipolarophiles for diastereoselective synthesis of spirooxindole pyrrolizidines are introduced. This one-pot synthesis involving five components generates a highly condensed ring system bearing seven stereocenters diastereoselectively. The new method has high pot, atom, and step economy. Only two equivalents of water are released as a side product.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Double (3 + 2) cycloadditions for diastereoselective synthesis of spirooxindole pyrrolizidines ; volume:11 ; number:1 ; year:2022 ; pages:1128-1135 ; extent:8
Green processing & synthesis ; 11, Heft 1 (2022), 1128-1135 (gesamt 8)
- Creator
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Zhang, Xiaofeng
Ma, Xiaoming
Qiu, Weiqi
Awad, JohnMark
Zhang, Wei
- DOI
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10.1515/gps-2022-0088
- URN
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urn:nbn:de:101:1-2022122013023666898316
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:20 AM CEST
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Associated
- Zhang, Xiaofeng
- Ma, Xiaoming
- Qiu, Weiqi
- Awad, JohnMark
- Zhang, Wei
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