Microfluidic Formation of Monodisperse Coacervate Organelles in Liposomes
Abstract: Coacervates have been widely studied as model compartments in protocell research. Complex coacervates composed of disordered proteins and RNA have also been shown to play an important role in cellular processes. Herein, we report on a microfluidic strategy for constructing monodisperse coacervate droplets encapsulated within uniform unilamellar liposomes. These structures represent a bottom‐up approach to hierarchically structured protocells, as demonstrated by storage and release of DNA from the encapsulated coacervates as well as localized transcription.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Microfluidic Formation of Monodisperse Coacervate Organelles in Liposomes ; volume:56 ; number:33 ; year:2017 ; pages:9736-9740 ; extent:5
Angewandte Chemie / International edition. International edition ; 56, Heft 33 (2017), 9736-9740 (gesamt 5)
- Creator
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Deng, Nan‐Nan
Huck, Wilhelm T. S.
- DOI
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10.1002/anie.201703145
- URN
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urn:nbn:de:101:1-2022091307085173808859
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:20 AM CEST
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Associated
- Deng, Nan‐Nan
- Huck, Wilhelm T. S.
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Microfluidic-assisted Formation of Highly Monodisperse and Mesoporous Silica Soft Microcapsules
Microfluidic preparation of monodisperse polymeric microspheres coated with silica nanoparticles
Machine learning instructed microfluidic synthesis of curcumin-loaded liposomes
Microfluidic vortex focusing for high throughput synthesis of size-tunable liposomes
Spatiotemporal control of coacervate formation within liposomes
Functionalized monodisperse microbubble production: microfluidic method for fast, controlled, and automated removal of excess coating material
Metabolic signalling between organelles
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Microfluidic-assisted Formation of Highly Monodisperse and Mesoporous Silica Soft Microcapsules
Microfluidic preparation of monodisperse polymeric microspheres coated with silica nanoparticles
Machine learning instructed microfluidic synthesis of curcumin-loaded liposomes
Microfluidic vortex focusing for high throughput synthesis of size-tunable liposomes
Spatiotemporal control of coacervate formation within liposomes
Functionalized monodisperse microbubble production: microfluidic method for fast, controlled, and automated removal of excess coating material
Metabolic signalling between organelles
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