Hepatic Histoplasmosis Masquerading as Cirrhosis and Portal Hypertension: A Case Report

Abstract: Histoplasmosis is an uncommon cause of pyrexia of unknown origin in India. We present a case of hepatic histoplasmosis presenting as pyrexia of unknown origin. The patient had splenomegaly, thrombocytopenia, high serum-ascites albumin gradient, and imaging suggestive of cirrhosis. The patient had received 2 months of antitubercular treatment and came to us because of a lack of improvement. A liver biopsy was done because of cholestatic liver function tests and normal biliary system on imaging, thus raising the possibility of infiltrative liver disease. A transjugular liver biopsy revealed histoplasmosis. The patients improved after treatment. It is a common practice to start antitubercular treatment in patients with pyrexia of unknown origin, which should not be practiced in the current era. Every effort should be made for a correct diagnosis. The case highlights the importance of liver biopsy in cases with no definite diagnosis and also that hepatic histoplasmosis could mimic cirrhosis.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Hepatic Histoplasmosis Masquerading as Cirrhosis and Portal Hypertension: A Case Report ; volume:12 ; number:02 ; year:2022 ; pages:121-123
Journal of Gastrointestinal Infections ; 12, Heft 02 (2022), 121-123

Contributor
Choudhary, Narendra Singh
Deswal, Vikas
Dhampalwar, Swapnil
Mishra, Saurabh
Gautam, Dheeraj
Saraf, Neeraj

DOI
10.1055/s-0042-1759744
URN
urn:nbn:de:101:1-2024030112002986673741
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
14.08.2025, 10:54 AM CEST

Data provider

This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.

Associated

  • Choudhary, Narendra Singh
  • Deswal, Vikas
  • Dhampalwar, Swapnil
  • Mishra, Saurabh
  • Gautam, Dheeraj
  • Saraf, Neeraj

Other Objects (12)