Metabolic pattern formation in the tumor microenvironment

Metabolic alterations including increased glycolysis are a common feature of many cancers. In their recent study, Lowengrub, Waterman, and colleagues (Lee et al, 2017) report a spatial pattern of glycolysis in solid tumors that occurs within the tumor microenvironment. This spatial organization is linked to gradients derived from Wnt signaling and nutrient availability that mediate a reaction‐diffusion mechanism and is consistent with a Turing‐type model of spatial localization.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
Metabolic pattern formation in the tumor microenvironment ; volume:13 ; number:2 ; year:2017 ; extent:2
Molecular systems biology ; 13, Heft 2 (2017) (gesamt 2)

Creator
Dai, Ziwei
Locasale, Jason W.

DOI
10.15252/msb.20167518
URN
urn:nbn:de:101:1-2022100608252602337990
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:29 AM CEST

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Associated

  • Dai, Ziwei
  • Locasale, Jason W.

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