Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity

to related objects

Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 1546-1696

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity ; day:10 ; month:11 ; year:2022 ; pages:1-13
Nature biotechnology ; (10.11.2022), 1-13

Creator: Neugebauer, Monica E.
Hsu, Alvin
Arbab, Mandana
Krasnow, Nicholas A.
McElroy, Amber N.
Pandey, Smriti
Doman, Jordan L.
Huang, Tony P.
Raguram, Aditya
Banskota, Samagya
Newby, Gregory A.
Tolar, Jakub
Osborn, Mark J.
Liu, David R.

Contributor: SpringerLink (Online service)

DOI: 10.1038/s41587-022-01533-6

URN: urn:nbn:de:101:1-2023012110284480474013

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:20 AM CEST

Data provider

This object is provided by:
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.

Show original at data provider

Associated

Neugebauer, Monica E.
Hsu, Alvin
Arbab, Mandana
Krasnow, Nicholas A.
McElroy, Amber N.
Pandey, Smriti
Doman, Jordan L.
Huang, Tony P.
Raguram, Aditya
Banskota, Samagya
Newby, Gregory A.
Tolar, Jakub
Osborn, Mark J.
Liu, David R.
SpringerLink (Online service)

Other Objects (12)

A split and inducible adenine base editor for precise in vivo base editing

Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors

Genome-wide profiling of adenine base editor specificity by EndoV-seq

Adenine base editor corrected ADPKD point mutations in hiPSCs and kidney organoids

ABE8e adenine base editor precisely and efficiently corrects a recurrent COL7A1 nonsense mutation

Targeting fidelity of adenine and cytosine base editors in mouse embryos

Engineered cytosine base editor enabling broad-scope and high-fidelity gene editing in Streptomyces

Cytosine base editing systems with minimized off-target effect and molecular size

Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation

Directed-evolution mutations enhance DNA-binding affinity and protein stability of the adenine base editor ABE8e

Docking sites inside Cas9 for adenine base editing diversification and RNA off-target elimination

Author Correction: Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation

A split and inducible adenine base editor for precise in vivo base editing

Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors

Genome-wide profiling of adenine base editor specificity by EndoV-seq

Adenine base editor corrected ADPKD point mutations in hiPSCs and kidney organoids

ABE8e adenine base editor precisely and efficiently corrects a recurrent COL7A1 nonsense mutation

Targeting fidelity of adenine and cytosine base editors in mouse embryos

Engineered cytosine base editor enabling broad-scope and high-fidelity gene editing in Streptomyces

Cytosine base editing systems with minimized off-target effect and molecular size

Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation

Directed-evolution mutations enhance DNA-binding affinity and protein stability of the adenine base editor ABE8e

Docking sites inside Cas9 for adenine base editing diversification and RNA off-target elimination

Author Correction: Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation

A split and inducible adenine base editor for precise in vivo base editing

Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors

Genome-wide profiling of adenine base editor specificity by EndoV-seq

Adenine base editor corrected ADPKD point mutations in hiPSCs and kidney organoids

ABE8e adenine base editor precisely and efficiently corrects a recurrent COL7A1 nonsense mutation

Targeting fidelity of adenine and cytosine base editors in mouse embryos

Engineered cytosine base editor enabling broad-scope and high-fidelity gene editing in Streptomyces

Cytosine base editing systems with minimized off-target effect and molecular size

Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation

Directed-evolution mutations enhance DNA-binding affinity and protein stability of the adenine base editor ABE8e

Docking sites inside Cas9 for adenine base editing diversification and RNA off-target elimination

Author Correction: Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation

Cultural heritage institutions wishing to register will find more information here.

Fields marked * need to be filled in.

Username*

Please enter your username

Email*

Please enter your email address

Please do not fill this field

First name

Last name

Password*

Please enter your password

Confirm password*

Please enter the same password

I have read the terms of use and the privacy policy for the collection of personal data and accept them. *

This field is required.

I would like to subscribe to the newsletter of the Deutsche Digitale Bibliothek. See newsletter subscription info.

Account created

Your "My DDB" account has been successfully created. Before you can log in to your account, you must click the confirmation link in the message we just sent to the email address you provided.

Evolution of an adenine base editor into a small, efficient cytosine base editor with low off-target activity

Object Details

References and Relationships

Contributors, Places and Time

Further information

Data provider

Associated

Other Objects (12)

A split and inducible adenine base editor for precise in vivo base editing

Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors

Genome-wide profiling of adenine base editor specificity by EndoV-seq

Adenine base editor corrected ADPKD point mutations in hiPSCs and kidney organoids

ABE8e adenine base editor precisely and efficiently corrects a recurrent COL7A1 nonsense mutation

Targeting fidelity of adenine and cytosine base editors in mouse embryos

Engineered cytosine base editor enabling broad-scope and high-fidelity gene editing in Streptomyces

Cytosine base editing systems with minimized off-target effect and molecular size

Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation

Directed-evolution mutations enhance DNA-binding affinity and protein stability of the adenine base editor ABE8e

Docking sites inside Cas9 for adenine base editing diversification and RNA off-target elimination

Author Correction: Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation

A split and inducible adenine base editor for precise in vivo base editing

Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors

Genome-wide profiling of adenine base editor specificity by EndoV-seq

Adenine base editor corrected ADPKD point mutations in hiPSCs and kidney organoids

ABE8e adenine base editor precisely and efficiently corrects a recurrent COL7A1 nonsense mutation

Targeting fidelity of adenine and cytosine base editors in mouse embryos

Engineered cytosine base editor enabling broad-scope and high-fidelity gene editing in Streptomyces

Cytosine base editing systems with minimized off-target effect and molecular size

Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation

Directed-evolution mutations enhance DNA-binding affinity and protein stability of the adenine base editor ABE8e

Docking sites inside Cas9 for adenine base editing diversification and RNA off-target elimination

Author Correction: Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation

A split and inducible adenine base editor for precise in vivo base editing

Multiplexed base editing through Cas12a variant-mediated cytosine and adenine base editors

Genome-wide profiling of adenine base editor specificity by EndoV-seq

Adenine base editor corrected ADPKD point mutations in hiPSCs and kidney organoids

ABE8e adenine base editor precisely and efficiently corrects a recurrent COL7A1 nonsense mutation

Targeting fidelity of adenine and cytosine base editors in mouse embryos

Engineered cytosine base editor enabling broad-scope and high-fidelity gene editing in Streptomyces

Cytosine base editing systems with minimized off-target effect and molecular size

Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation

Directed-evolution mutations enhance DNA-binding affinity and protein stability of the adenine base editor ABE8e

Docking sites inside Cas9 for adenine base editing diversification and RNA off-target elimination

Author Correction: Engineering TadA ortholog-derived cytosine base editor without motif preference and adenosine activity limitation

Related objects

Reset password