Syndromic craniosynostosis: neuropsycholinguistic abilities and imaging analysis of the central nervous system

Abstract: Objective: To characterize patients with syndromic craniosynostosis with respect to their neuropsycholinguistic abilities and to present these findings together with the brain abnormalities. Methods: Eighteen patients with a diagnosis of syndromic craniosynostosis were studied. Eight patients had Apert syndrome and 10 had Crouzon syndrome. They were submitted to phonological evaluation, neuropsychological evaluation and magnetic resonance imaging of the brain. The phonological evaluation was done by behavioral observation of the language, the Peabody test, Token test and a school achievement test. The neuropsychological evaluation included the WISC III and WAIS tests. Results: Abnormalities in language abilities were observed and the school achievement test showed abnormalities in 66.67% of the patients. A normal intelligence quotient was observed in 39.3% of the patients, and congenital abnormalities of the central nervous system were observed in 46.4% of the patients. Conclusion: Abnormalities of language abilities were observed in the majority of patients with syndromic craniosynostosis, and low cognitive performance was also observed.

Object Details

• Alternative title: Craniossinostoses sindrçmicas: habilidades neuropsicolinguísticas e análise por imagem do sistema nervoso central
• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Syndromic craniosynostosis: neuropsycholinguistic abilities and imaging analysis of the central nervous system ; volume:75 ; number:12 ; year:2017 ; pages:862-868 ; Arquivos de neuro-psiquiatria ; 75, Heft 12 (2017), 862-868

Contributors, Places and Time

• Contributor: Maximino, Luciana Paula ; Ducati, Luis Gustavo ; Abramides, Dagma Venturini Marques ; Corrêa, Camila de Castro ; Garcia, Patrícia Fernandes ; Fernandes, Adriano Yacubian

Further information

• DOI: 10.1590/0004-282X20170171
• URN: urn:nbn:de:101:1-2023101910212439482810
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 14.08.2025, 10:49 AM CEST