ENDOSCOPIC VACUUM THERAPY FOR ANASTOMOTIC LEAKAGE AFTER UPPER GASTROINTESTINAL SURGERY

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Background and study aim: Recently, endoscopic vacuum therapy (EVT) was introduced as treatment for anastomotic leakage (AL) after upper gastrointestinal (GI) surgery. Aim of this study was to describe the initial experiences with EVT for AL after upper GI surgery in a tertiary referral center. Patients and methods: Patients treated with EVT for AL after upper GI surgery were included retrospectively (January 2018-June 2021) and prospectively (June 2021-October 2021). The primary endpoint was EVT success rate. Secondary endpoints included mortality and adverse events. Results: 38 patients were included (31 men, mean age 66 years). 27 patients had undergone an esophagectomy with gastric conduit reconstruction and 11 a total gastrectomy with esophago-jejunal anastomosis. EVT was successful in 28 patients (74%, 95% CI [57-87]). In 10 patients EVT failed: 1 deceased due to radiation pneumonitis, 2 had EVT-associated complications and in 7 defect closure was not achieved. Mean duration of successful EVT was 27 days, with median 6 EVT-related endoscopies. Median hospital stay was 45 days. Conclusion: This initial experience with EVT for anastomotic leakage after upper GI surgery demonstrated a success rate of 74%. EVT is a promising therapy that could prevent major re-surgery. More experience with the technique and its indications will likely improve success rates in the future.

Location: Deutsche Nationalbibliothek Frankfurt am Main

Extent: Online-Ressource

Language: Englisch

Bibliographic citation: ENDOSCOPIC VACUUM THERAPY FOR ANASTOMOTIC LEAKAGE AFTER UPPER GASTROINTESTINAL SURGERY ; day:30 ; month:05 ; year:2023
Endoscopy ; (30.05.2023)

Contributor: Pattynama, Lisanne M.D.
Pouw, Roos E.
van Berge Henegouwen, Mark I.
Daams, Freek
Gisbertz, Suzanne
Bergman, Jacques JGHM
Eshuis, Wietse

DOI: 10.1055/a-2102-1691

URN: urn:nbn:de:101:1-2023071311492721763775

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 14.08.2025, 10:49 AM CEST

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Pattynama, Lisanne M.D.
Pouw, Roos E.
van Berge Henegouwen, Mark I.
Daams, Freek
Gisbertz, Suzanne
Bergman, Jacques JGHM
Eshuis, Wietse

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