Neutrophil gelatinase-associated lipocalin as a risk marker in cardiovascular disease
Abstract: Neutrophil gelatinase-associated lipocalin (NGAL) is a promising diagnostic biomarker of early acute kidney injury. Increasing evidence suggests that NGAL may also be involved in inflammatory processes in cardiovascular disease. NGAL modulates the enzymatic activity of matrix metalloproteinase-9 (MMP-9), which is an important mediator of plaque instability in atherosclerosis. The complex formation between NGAL and MMP-9 therefore suggests that NGAL might play a role in progression of atherothrombotic disease. This review summarises current data on NGAL in atherosclerosis, acute myocardial infarction, and heart failure.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Neutrophil gelatinase-associated lipocalin as a risk marker in cardiovascular disease ; volume:56 ; number:1 ; year:2017 ; pages:5-18 ; extent:14
Clinical chemistry and laboratory medicine ; 56, Heft 1 (2017), 5-18 (gesamt 14)
- Creator
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Sivalingam, Zenthuja
Larsen, Sanne Bøjet
Grove, Erik Lerkevang
Hvas, Anne-Mette
Kristensen, Steen Dalby
Magnusson, Nils Erik
- DOI
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10.1515/cclm-2017-0120
- URN
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urn:nbn:de:101:1-2022052708334083509453
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:28 AM CEST
Data provider
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Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Sivalingam, Zenthuja
- Larsen, Sanne Bøjet
- Grove, Erik Lerkevang
- Hvas, Anne-Mette
- Kristensen, Steen Dalby
- Magnusson, Nils Erik
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