Computational study of ventricular fibrillation by considering a strongly coupled electromechanical rat heart model

Abstract: Fully coupled electromechanical models of the heart have demonstrated the importance of computational models to better understand the cause, evolution and termination of ventricular fibrillation (VF). Especially these kinds of models are used to study the interplay between the mechanoelectrical feedback (MEF) and VF. In this study, we investigate the influence of the MEF in a strongly coupled excitation‐contraction model on the VF behaviour of a MRI based rat left ventricle (LV) by varying the maximum conductance of the stretch activated channels (SACs). We finally compare the action potential (AP) evolution and apex displacement under different strengths of the MEF.

Angaben zum Objekt

• Standort: Deutsche Nationalbibliothek Frankfurt am Main
• Umfang: Online-Ressource
• Sprache: Englisch

Verweise und Beziehungen

• Erschienen in: Computational study of ventricular fibrillation by considering a strongly coupled electromechanical rat heart model ; volume:19 ; number:1 ; year:2019 ; extent:2 ; Proceedings in applied mathematics and mechanics ; 19, Heft 1 (2019) (gesamt 2)

Beteiligte, Orts- und Zeitangaben

• Urheber: Holz, David ; Duong, Minh Tuan ; Alkassar, Muhannad ; Dittrich, Sven ; Leyendecker, Sigrid

Weitere Informationen

• DOI: 10.1002/pamm.201900227
• URN: urn:nbn:de:101:1-2022072208440502446023
• Rechteinformation: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Letzte Aktualisierung: 15.08.2025, 07:29 MESZ