Recent Advances in Visible Light‐Mediated Radical Fluoro‐alkylation, ‐alkoxylation, ‐alkylthiolation, ‐alkylselenolation, and ‐alkylamination
Abstract: In the last few years, many reagents and protocols have been developed to allow for the efficient fluorofunctionalization of a diverse set of scaffolds ranging from alkanes, alkenes, alkynes, and (hetero) arenes. The concomitant rise of organofluorine chemistry and visible light‐mediated synthesis have synergistically expanded the fields and have mutually benefitted from developments in both fields. In this context, visible light driven formations of radicals containing fluorine have been a major focus for the discovery of new bioactive compounds. This review details the recent advances and progress made in visible light‐mediated fluoroalkylation and heteroatom centered radical generation.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Recent Advances in Visible Light‐Mediated Radical Fluoro‐alkylation, ‐alkoxylation, ‐alkylthiolation, ‐alkylselenolation, and ‐alkylamination ; day:22 ; month:05 ; year:2023 ; extent:36
The chemical record ; (22.05.2023) (gesamt 36)
- Creator
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Lin, Daniel
Coe, Matthew
Krishnamurti, Vinayak
Ispizua‐Rodriguez, Xanath
Surya Prakash, G. K.
- DOI
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10.1002/tcr.202300104
- URN
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urn:nbn:de:101:1-2023052215172895277381
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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14.08.2025, 10:57 AM CEST
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Associated
- Lin, Daniel
- Coe, Matthew
- Krishnamurti, Vinayak
- Ispizua‐Rodriguez, Xanath
- Surya Prakash, G. K.
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Correction to: Advances in the automated synthesis of 6-[18F]Fluoro-L-DOPA
Visible‐Light‐Mediated Controlled Radical Branching Polymerization in Water
Advancements in Visible-Light-Enabled Radical C(sp)2–H Alkylation of (Hetero)arenes
Asymmetric allylic alkylation of Morita–Baylis–Hillman carbonates with α-fluoro-β-keto esters
Advances in the automated synthesis of 6-[18F]Fluoro-L-DOPA
Development of an Enantioselective Allylic Alkylation of Acyclic α ‐Fluoro‐ β ‐ketoesters for Asymmetric Synthesis of 3‐Fluoropiperidines
Advances in radical peroxidation with hydroperoxides
Visible Light Thiyl Radical‐Mediated Desilylation of Arylsilanes
A third generation of radical fluorinating agents based on N-fluoro-N-arylsulfonamides
The First Practical Additive-Free 1,4-Conjugated Alkylation of Fluoroalkylated Electron-Deficient Olefins with Various Organozinc Reagents
Efficient Radical‐Mediated Intermolecular α‐Alkylation Reactions of Carbonyl Compounds with Nonactivated Alkenes
Electrochemical halogen-atom transfer alkylation via α-aminoalkyl radical activation of alkyl iodides
Correction to: Advances in the automated synthesis of 6-[18F]Fluoro-L-DOPA
Visible‐Light‐Mediated Controlled Radical Branching Polymerization in Water
Advancements in Visible-Light-Enabled Radical C(sp)2–H Alkylation of (Hetero)arenes
Asymmetric allylic alkylation of Morita–Baylis–Hillman carbonates with α-fluoro-β-keto esters
Advances in the automated synthesis of 6-[18F]Fluoro-L-DOPA
Development of an Enantioselective Allylic Alkylation of Acyclic α ‐Fluoro‐ β ‐ketoesters for Asymmetric Synthesis of 3‐Fluoropiperidines
Advances in radical peroxidation with hydroperoxides
Visible Light Thiyl Radical‐Mediated Desilylation of Arylsilanes
A third generation of radical fluorinating agents based on N-fluoro-N-arylsulfonamides
The First Practical Additive-Free 1,4-Conjugated Alkylation of Fluoroalkylated Electron-Deficient Olefins with Various Organozinc Reagents
Efficient Radical‐Mediated Intermolecular α‐Alkylation Reactions of Carbonyl Compounds with Nonactivated Alkenes
Electrochemical halogen-atom transfer alkylation via α-aminoalkyl radical activation of alkyl iodides
Correction to: Advances in the automated synthesis of 6-[18F]Fluoro-L-DOPA