A Concept Formula With Large, Milk Phospholipid‐Coated Lipid Droplets Enriched With Milk Fat Decreases Palmitic Acid and Calcium Levels in Stools of Healthy, Term Infants
Abstract: This study evaluates the impact of an infant formula comprising large, dairy milk phospholipid‐coated lipid droplets containing a vegetable‐dairy lipid mixture (Concept‐Mix) with 6% of fatty acid (FA) as sn‐2 palmitic acid (PA) on infant stool characteristics. Stool samples from infants fed Concept‐Mix or standard formula with 97% vegetable lipids with 2% of FA as sn‐2 PA (Control‐Veg) are evaluated at baseline, 13 and 52 weeks of age. Overall, mean stool fat content decreases from 8 to 10 w% at baseline to <2 w% at 52 weeks. At 13 weeks, PA and Calcium (Ca) content, as well as FA sum are lower in Concept‐Mix than Control‐Veg stools, with values closer to breastfed infants. The increased dietary sn‐2 PA content is regarded as instrumental for this fecal PA reduction. Indeed, in their proof of principle study in rats fed formula‐based diets using Control‐Veg, Concept‐Mix, or Concept formula with 95% vegetable lipids (Concept‐Veg) comprising 2%, 6%, and 2% of FA as sn‐2 PA, they demonstrate that PA absorption is the highest for Concept‐Mix. Hence, a concept formula with large, milk phospholipid coated lipid droplets enriched with milk fat beneficially affects PA and Ca absorption in infants, likely due to its increased sn‐2 PA content. Practical applications: The results of these studies show the merit with regard to sn‐2 palmitic acid (PA) and Calci absorption of increasing the sn‐2 PA content in the fat blend of infant formula by including dairy milk fat.
- Location
-
Deutsche Nationalbibliothek Frankfurt am Main
- Extent
-
Online-Ressource
- Language
-
Englisch
- Bibliographic citation
-
A Concept Formula With Large, Milk Phospholipid‐Coated Lipid Droplets Enriched With Milk Fat Decreases Palmitic Acid and Calcium Levels in Stools of Healthy, Term Infants ; day:20 ; month:09 ; year:2022 ; extent:12
European journal of lipid science and technology ; (20.09.2022) (gesamt 12)
- Creator
-
van de Heijning, Bert J. M.
Schoen, Stefanie
Abrahamse‐Berkeveld, Marieke
Hokken‐Koelega, Anita C. S.
van der Beek, Eline M.
- DOI
-
10.1002/ejlt.202200018
- URN
-
urn:nbn:de:101:1-2022092115144537611186
- Rights
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
-
15.08.2025, 7:22 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- van de Heijning, Bert J. M.
- Schoen, Stefanie
- Abrahamse‐Berkeveld, Marieke
- Hokken‐Koelega, Anita C. S.
- van der Beek, Eline M.
Other Objects (12)
Formula with large, milk phospholipid-coated lipid droplets in late-moderate preterm infants: a double-blind RCT
Milk microbiome transplantation: recolonizing donor milk with mother's own milk microbiota
Comprehensive and quantitative profiling of lipid species in human milk, cow milk and a phospholipid‐enriched milk formula by GC and MS/MS ALL
Role of Phospholipid Flux during Milk Secretion in the Mammary Gland
MILK
MILK
Milk
Milk and lactation : with 32 tables
Prospective evaluation of testing with baked milk to predict safe ingestion of baked milk in unheated milk-allergic children
Maternal diet alters human milk oligosaccharide composition with implications for the milk metagenome
Milk market after abolition of milk quotas
Milk and milk products in human nutrition
Formula with large, milk phospholipid-coated lipid droplets in late-moderate preterm infants: a double-blind RCT
Milk microbiome transplantation: recolonizing donor milk with mother's own milk microbiota
Comprehensive and quantitative profiling of lipid species in human milk, cow milk and a phospholipid‐enriched milk formula by GC and MS/MS ALL
Role of Phospholipid Flux during Milk Secretion in the Mammary Gland
MILK
MILK
Milk
Milk and lactation : with 32 tables
Prospective evaluation of testing with baked milk to predict safe ingestion of baked milk in unheated milk-allergic children
Maternal diet alters human milk oligosaccharide composition with implications for the milk metagenome
Milk market after abolition of milk quotas
Milk and milk products in human nutrition
Formula with large, milk phospholipid-coated lipid droplets in late-moderate preterm infants: a double-blind RCT
Milk microbiome transplantation: recolonizing donor milk with mother's own milk microbiota
Comprehensive and quantitative profiling of lipid species in human milk, cow milk and a phospholipid‐enriched milk formula by GC and MS/MS ALL
Role of Phospholipid Flux during Milk Secretion in the Mammary Gland
MILK
MILK
Milk
Milk and lactation : with 32 tables
Prospective evaluation of testing with baked milk to predict safe ingestion of baked milk in unheated milk-allergic children
Maternal diet alters human milk oligosaccharide composition with implications for the milk metagenome
Milk market after abolition of milk quotas