Energy landscape reshaped by strain-specific mutations underlies epistasis in NS1 evolution of influenza A virus

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Location: Deutsche Nationalbibliothek Frankfurt am Main

ISSN: 2041-1723

Extent: Online-Ressource

Language: Englisch

Notes: online resource.

Bibliographic citation: Energy landscape reshaped by strain-specific mutations underlies epistasis in NS1 evolution of influenza A virus ; volume:13 ; number:1 ; day:1 ; month:10 ; year:2022 ; pages:1-13 ; date:12.2022
Nature Communications ; 13, Heft 1 (1.10.2022), 1-13, 12.2022

Creator: Kim, Iktae
Dubrow, Alyssa
Zuniga, Bryan
Zhao, Baoyu
Sherer, Noah
Bastiray, Abhishek
Li, Pingwei
Cho, Jae-Hyun

Contributor: SpringerLink (Online service)

DOI: 10.1038/s41467-022-33554-9

URN: urn:nbn:de:101:1-2022122021261664820719

Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.

Last update: 15.08.2025, 7:20 AM CEST

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Associated

Kim, Iktae
Dubrow, Alyssa
Zuniga, Bryan
Zhao, Baoyu
Sherer, Noah
Bastiray, Abhishek
Li, Pingwei
Cho, Jae-Hyun
SpringerLink (Online service)

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Effects of mutations in the effector domain of influenza A virus NS1 protein

Influenza A virus NS1 gene mutations F103L and M106I increase replication and virulence

Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replication

Unexpected functional divergence of bat influenza virus NS1 proteins

Protein destabilization underlies pathogenic missense mutations in ARID1B

Influenza C virus NS1 protein counteracts RIG-I-mediated IFN signalling

Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition

Compensatory mutations cause excess of antagonistic epistasis in RNA secondary structure folding

Heterologous interactions between NS1 proteins from different influenza A virus subtypes/strains

Interaction of influenza virus NS1 protein with growth arrest-specific protein 8

Analysis of the PDZ binding specificities of Influenza A Virus NS1 proteins

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Effects of mutations in the effector domain of influenza A virus NS1 protein

Influenza A virus NS1 gene mutations F103L and M106I increase replication and virulence

Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replication

Unexpected functional divergence of bat influenza virus NS1 proteins

Protein destabilization underlies pathogenic missense mutations in ARID1B

Influenza C virus NS1 protein counteracts RIG-I-mediated IFN signalling

Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition

Compensatory mutations cause excess of antagonistic epistasis in RNA secondary structure folding

Heterologous interactions between NS1 proteins from different influenza A virus subtypes/strains

Interaction of influenza virus NS1 protein with growth arrest-specific protein 8

Analysis of the PDZ binding specificities of Influenza A Virus NS1 proteins

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Energy landscape reshaped by strain-specific mutations underlies epistasis in NS1 evolution of influenza A virus

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Other Objects (12)

Effects of mutations in the effector domain of influenza A virus NS1 protein

Influenza A virus NS1 gene mutations F103L and M106I increase replication and virulence

Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replication

Unexpected functional divergence of bat influenza virus NS1 proteins

Protein destabilization underlies pathogenic missense mutations in ARID1B

Influenza C virus NS1 protein counteracts RIG-I-mediated IFN signalling

Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition

Compensatory mutations cause excess of antagonistic epistasis in RNA secondary structure folding

Heterologous interactions between NS1 proteins from different influenza A virus subtypes/strains

Interaction of influenza virus NS1 protein with growth arrest-specific protein 8

Analysis of the PDZ binding specificities of Influenza A Virus NS1 proteins

N.S.1: Revue égyptologique

Effects of mutations in the effector domain of influenza A virus NS1 protein

Influenza A virus NS1 gene mutations F103L and M106I increase replication and virulence

Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replication

Unexpected functional divergence of bat influenza virus NS1 proteins

Protein destabilization underlies pathogenic missense mutations in ARID1B

Influenza C virus NS1 protein counteracts RIG-I-mediated IFN signalling

Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition

Compensatory mutations cause excess of antagonistic epistasis in RNA secondary structure folding

Heterologous interactions between NS1 proteins from different influenza A virus subtypes/strains

Interaction of influenza virus NS1 protein with growth arrest-specific protein 8

Analysis of the PDZ binding specificities of Influenza A Virus NS1 proteins

N.S.1: Revue égyptologique

Effects of mutations in the effector domain of influenza A virus NS1 protein

Influenza A virus NS1 gene mutations F103L and M106I increase replication and virulence

Mutations within the conserved NS1 nuclear export signal lead to inhibition of influenza A virus replication

Unexpected functional divergence of bat influenza virus NS1 proteins

Protein destabilization underlies pathogenic missense mutations in ARID1B

Influenza C virus NS1 protein counteracts RIG-I-mediated IFN signalling

Molecular mechanism of influenza A NS1-mediated TRIM25 recognition and inhibition

Compensatory mutations cause excess of antagonistic epistasis in RNA secondary structure folding

Heterologous interactions between NS1 proteins from different influenza A virus subtypes/strains

Interaction of influenza virus NS1 protein with growth arrest-specific protein 8

Analysis of the PDZ binding specificities of Influenza A Virus NS1 proteins

N.S.1: Revue égyptologique

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