Granulomatous hypophysitis caused by Rathke's cleft cyst mimicking a growth hormone-secreting pituitary adenoma
We report a case of granulomatous hypophysitis caused by Rathke's cleft cyst (RCC) mimicking a growth hormone (GH)-secreting pituitary adenoma. Neuroradiological and endocrinological evaluations showed abnormal findings consistent with acromegaly: Magnetic resonance imaging demonstrated a pituitary mass lesion, and GH and insulin-like growth factor I levels were markedly elevated, and GH levels were not suppressed in oral glucose tolerance test. Transsphenoidal surgery was performed, but no adenomatous tissue could be detected. Histological examination revealed RCC and concurrent granulomatous giant cell inflammatory reaction of the anterior hypophysis. To the authors' knowledge, this is the first documented case of granulomatous hypophysitis caused by RCC mimicking a GH-secreting pituitary adenoma.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Granulomatous hypophysitis caused by Rathke's cleft cyst mimicking a growth hormone-secreting pituitary adenoma ; volume:12 ; number:02 ; year:2017 ; pages:283-286
Asian journal of neurosurgery ; 12, Heft 02 (2017), 283-286
- Contributor
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Hojo, Masato
Ishibashi, Ryota
Arai, Hiroshi
Miyamoto, Susumu
- DOI
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10.4103/1793-5482.146390
- URN
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urn:nbn:de:101:1-2022112412162595864038
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:33 AM CEST
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Associated
- Hojo, Masato
- Ishibashi, Ryota
- Arai, Hiroshi
- Miyamoto, Susumu
Other Objects (12)
Coexisting Rathke Cleft Cyst and Pituitary Adenoma Presenting with Pituitary Apoplexy: Report of Two Cases
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Intrasellar Rathke’s Cleft Cyst and Acromegaly: an Unusual Coincidence : One Sentence Summary: Dual sellar lesions are relatively uncommon. Asymptomatic Rathke’s cleft cyst, a relatively common entity, in concurrence with a pituitary adenoma, should be considered in the differential diagnosis of two distinct pituitary lesions.
EpCAM (CD326) is differentially expressed in craniopharyngioma subtypes and Rathke’s cleft cysts
Rathke’s cleft cyst discovered with ruptured anterior communicating artery aneurysm: a case report
Localization of TSH-secreting pituitary adenoma using 11C-methionine image subtraction
Rathke's Cleft Cyst as Origin of a Pediatric Papillary Craniopharyngioma
An entirely suprasellar Rathke’s cleft cyst: a rare case report with review of literature
Intraparenchymal infiltration of Rathke’s cleft cysts manifesting as severe neurological deficits and hypopituitarism: 2 case reports
Ectopic sphenoidal ACTH-secreting adenoma revealed by 11C Methionine PET scan: case report
Global changes in chromatin accessibility and transcription in growth hormone-secreting pituitary adenoma
Coexisting Rathke Cleft Cyst and Pituitary Adenoma Presenting with Pituitary Apoplexy: Report of Two Cases
Rathke’s Cleft Cyst Abscess—An Unusual Guest in The Sella
Rathke's Cleft Cyst Abscess with a Very Unusual Course
Intrasellar Rathke’s Cleft Cyst and Acromegaly: an Unusual Coincidence : One Sentence Summary: Dual sellar lesions are relatively uncommon. Asymptomatic Rathke’s cleft cyst, a relatively common entity, in concurrence with a pituitary adenoma, should be considered in the differential diagnosis of two distinct pituitary lesions.
EpCAM (CD326) is differentially expressed in craniopharyngioma subtypes and Rathke’s cleft cysts
Rathke’s cleft cyst discovered with ruptured anterior communicating artery aneurysm: a case report
Localization of TSH-secreting pituitary adenoma using 11C-methionine image subtraction
Rathke's Cleft Cyst as Origin of a Pediatric Papillary Craniopharyngioma
An entirely suprasellar Rathke’s cleft cyst: a rare case report with review of literature
Intraparenchymal infiltration of Rathke’s cleft cysts manifesting as severe neurological deficits and hypopituitarism: 2 case reports
Ectopic sphenoidal ACTH-secreting adenoma revealed by 11C Methionine PET scan: case report
Global changes in chromatin accessibility and transcription in growth hormone-secreting pituitary adenoma
Coexisting Rathke Cleft Cyst and Pituitary Adenoma Presenting with Pituitary Apoplexy: Report of Two Cases
Rathke’s Cleft Cyst Abscess—An Unusual Guest in The Sella
Rathke's Cleft Cyst Abscess with a Very Unusual Course
Intrasellar Rathke’s Cleft Cyst and Acromegaly: an Unusual Coincidence : One Sentence Summary: Dual sellar lesions are relatively uncommon. Asymptomatic Rathke’s cleft cyst, a relatively common entity, in concurrence with a pituitary adenoma, should be considered in the differential diagnosis of two distinct pituitary lesions.
EpCAM (CD326) is differentially expressed in craniopharyngioma subtypes and Rathke’s cleft cysts
Rathke’s cleft cyst discovered with ruptured anterior communicating artery aneurysm: a case report
Localization of TSH-secreting pituitary adenoma using 11C-methionine image subtraction
Rathke's Cleft Cyst as Origin of a Pediatric Papillary Craniopharyngioma
An entirely suprasellar Rathke’s cleft cyst: a rare case report with review of literature
Intraparenchymal infiltration of Rathke’s cleft cysts manifesting as severe neurological deficits and hypopituitarism: 2 case reports
Ectopic sphenoidal ACTH-secreting adenoma revealed by 11C Methionine PET scan: case report