The structural biology of the shelterin complex

Abstract: The shelterin complex protects telomeric DNA and plays critical roles in maintaining chromosome stability. The structures and functions of the shelterin complex have been extensively explored in the past decades. This review summarizes the current progress on structural studies of shelterin complexes from different species. It focuses on the structural features and assembly of common structural domains, highlighting the evolutionary plasticity and conserved roles of shelterin proteins in telomere homeostasis and protection.

Location
Deutsche Nationalbibliothek Frankfurt am Main
Extent
Online-Ressource
Language
Englisch

Bibliographic citation
The structural biology of the shelterin complex ; volume:400 ; number:4 ; year:2019 ; pages:457-466 ; extent:10
Biological chemistry ; 400, Heft 4 (2019), 457-466 (gesamt 10)

Creator
Chen, Yong

DOI
10.1515/hsz-2018-0368
URN
urn:nbn:de:101:1-2022102714033186128449
Rights
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
Last update
15.08.2025, 7:36 AM CEST

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Associated

  • Chen, Yong

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