Synthesis of Piperazin-2-one Derivatives via Cascade Double Nucleophilic Substitution
A cascade, metal-promoted transformation utilizing chloro allenylamide, primary amine, and aryl iodide afforded piperizinones in good yields. Under the optimized conditions the cascade is performed as a one-pot process allowing the formation of three bonds. The synthetic route, controlled by the reaction rates of several processes involved, introduces two points of diversity and is well suited for combinatorial synthesis or related technologies.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Synthesis of Piperazin-2-one Derivatives via Cascade Double Nucleophilic Substitution ; volume:56 ; number:03 ; year:2024 ; pages:418-426
Synthesis ; 56, Heft 03 (2024), 418-426
- Beteiligte Personen und Organisationen
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Petkovic, Milos
Kusljevic, Dušica
Jovanovic, Milos
Jovanovic, Predrag
Tasic, Gordana
Simic, Milena
Savic, Vladimir
- DOI
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10.1055/a-2201-9951
- URN
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urn:nbn:de:101:1-2024022910154176605528
- Rechteinformation
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Kein Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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14.08.2025, 10:58 MESZ
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Beteiligte
- Petkovic, Milos
- Kusljevic, Dušica
- Jovanovic, Milos
- Jovanovic, Predrag
- Tasic, Gordana
- Simic, Milena
- Savic, Vladimir
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