Cyclic stress-strain behavior of polymeric nonwoven structures for the use as artificial leaflet material for transcatheter heart valve prostheses
Abstract: Xenogenic leaflet material, bovine and porcine pericardium, is widely used for the fabrication of surgically implanted and transcatheter heart valve prostheses. As a biological material, long term durability of pericardium is limited due to calcification, degeneration and homogeneity. Therefore, polymeric materials represent a promising approach for a next generation of artificial heart valve leaflets with improved durability. Within the current study we analyzed the mechanical performance of polymeric structures based on elastomeric materials. Polymeric cast films were prepared and nonwovens were manufactured in an electrospinning process. Analysis of cyclic stress-strain behavior was performed, using a universal testing machine. The uniaxial cyclic tensile experiments of the elastomeric samples yielded a non-linear elastic response due to viscoelastic behavior with hysteresis. Equilibrium of stress-strain curves was found after a specific number of cycles, for cast films and nonwovens, respectively. In conclusion, preconditioning was found obligatory for the evaluation of the mechanical performance of polymeric materials for the use as artificial leaflet material for heart valve prostheses.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Cyclic stress-strain behavior of polymeric nonwoven structures for the use as artificial leaflet material for transcatheter heart valve prostheses ; volume:3 ; number:2 ; year:2017 ; pages:703-706 ; extent:4
Current directions in biomedical engineering ; 3, Heft 2 (2017), 703-706 (gesamt 4)
- Creator
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Arbeiter, Daniela
Brandt-Wunderlich, Christoph
Siewert, Stefan
Kohse, Stefanie
Pfensig, Sylvia
Schmitz, Klaus-Peter
Grabow, Niels
- DOI
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10.1515/cdbme-2017-0149
- URN
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urn:nbn:de:101:1-2023030713141826016801
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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14.08.2025, 10:59 AM CEST
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Associated
- Arbeiter, Daniela
- Brandt-Wunderlich, Christoph
- Siewert, Stefan
- Kohse, Stefanie
- Pfensig, Sylvia
- Schmitz, Klaus-Peter
- Grabow, Niels
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Perspektiven aus den Technikwissenschaften bzw. der Medizintechnik
Plädoyer für Forschungsverbünde in der Wissenschaft : Perspektiven aus den Technikwissenschaften und der Medizintechnik
Reconstruction of biological functions: novel implant concepts for cardiovascular, ophthal-mologic and otolaryngologic applications : Current research and development activities of the Twenty20 consortium RESPONSE
Analysis on the effects of hypo-attenuated leaflet thickening on the hemodynamics of transcatheter aortic valve prostheses by means of particle image velocimetry
Influence of leaflet geometry on hydrodynamic performance of transcatheter aortic valve prostheses
Development of a constitutive law for numerical simulation of artificial leaflet-structures for transcatheter heart valve prostheses
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Permeability and wettability of bioresorbable nanofiber nonwoven membranes
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