Obstetrical Management of Severe Hypertriglyceridemia in Pregnancy: A Case Report
Abstract: Background Pregnant people with baseline hypertriglyceridemia are at increased risk of severe hypertriglyceridemia and the associated complications, yet there are no formal recommendations to guide management of these patients during pregnancy. Case We report a case of a patient with presumed familial hypertriglyceridemia who was taken off triglyceride-lowering medications preconception and developed acute pancreatitis at 23 weeks of gestation. She was managed with a very-low-fat diet, exercise, fenofibrate, omega-3-fatty acids, pravastatin, insulin infusion, and plasmapheresis. She delivered at 33 weeks of gestation after presenting with a placental abruption and subcapsular liver hematoma associated with HELLP (hemolysis, elevated liver enzyme levels, and low platelet) syndrome. Conclusion While rare in pregnancy, severe hypertriglyceridemia is associated with serious maternal risks. Preconception and antepartum obstetric management should incorporate shared decision-making considering both the potential fetal risks of treatment and the objective maternal risks of untreated disease.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Obstetrical Management of Severe Hypertriglyceridemia in Pregnancy: A Case Report ; volume:14 ; number:04 ; year:2024 ; pages:e244-e249
AJP reports ; 14, Heft 04 (2024), e244-e249
- Beteiligte Personen und Organisationen
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Madden, Nigel
Kamal, Nevin
Friedman, Jared
Freaney, Priya
Gerber, Susan E.
Szmuilowicz, Emily D.
- DOI
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10.1055/a-2413-2465
- URN
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urn:nbn:de:101:1-2412191049483.955021628947
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
- 2025-08-15T07:23:06+0200
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Madden, Nigel
- Kamal, Nevin
- Friedman, Jared
- Freaney, Priya
- Gerber, Susan E.
- Szmuilowicz, Emily D.
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