Cyclin A2: a genuine cell cycle regulator?

Abstract: Cyclin A2 belongs to the core cell cycle regulators and participates in the control of both S phase and mitosis. However, several observations suggest that it is also endowed with other functions, and our recent data shed light on its involvement in cytoskeleton dynamic and cell motility. From the transcription of its gene to its posttranslational modifications, cyclin A2 regulation reveals the complexity of the regulatory network shaping cell cycle progression. We summarize our current knowledge on this cell cycle regulator and discuss recent findings raising the possibility that cyclin A2 might play a much broader role in epithelial tissues homeostasis.

Object Details

• Location: Deutsche Nationalbibliothek Frankfurt am Main
• Extent: Online-Ressource
• Language: Englisch

References and Relationships

• Bibliographic citation: Cyclin A2: a genuine cell cycle regulator? ; volume:3 ; number:6 ; year:2012 ; pages:535-543 ; Biomolecular concepts ; 3, Heft 6 (2012), 535-543

Contributors, Places and Time

• Creator: Bendris, Nawal ; Loukil, Abdelhalim ; Cheung, Caroline ; Arsic, Nikola ; Rebouissou, Cosette ; Hipskind, Robert ; Peter, Marion ; Lemmers, Bénédicte ; Blanchard, Jean Marie

Further information

• DOI: 10.1515/bmc-2012-0027
• URN: urn:nbn:de:101:1-2409241624517.022610672269
• Rights: Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
• Last update: 15.08.2025, 7:26 AM CEST