Labrune Syndrome: A Very Rare Association of Leukoencephalopathy, Cerebral Calcifications, and Cysts
Abstract: Leukoencephalopathy, cerebral calcifications, and cysts (LCC) form a very rare association which is named as “Labrune syndrome” after Labrune who reported the first case in 1996. To the best of our knowledge only eight to 10 cases have been reported in literature to date. We report a case of a 26-year-old male with onset of neurological symptoms in late adolescence (at 19 years of age) and presented with complains of continued seizures for 7 years, giddiness with imbalance, and slowly progressive motor symptoms. MRI brain revealed multiple calcifications in bilateral basal ganglia, cerebral white matter, multiple cystic lesions in the supratentorial white matter, and abnormal diffused bilateral white matter T2 hyperintensity suggesting leukoencephalopathy. Histopathological evaluation revealed prominent congested blood vessels suggestive of angiomatous changes and cystic areas suggestive of secondary gliosis.
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Erschienen in
-
Labrune Syndrome: A Very Rare Association of Leukoencephalopathy, Cerebral Calcifications, and Cysts ; volume:31 ; number:03 ; year:2021 ; pages:772-775
The Indian journal of radiology and imaging ; 31, Heft 03 (2021), 772-775
- Beteiligte Personen und Organisationen
-
Joshi, Anagha R.
Kulkarni, Kiran
Shah, Ankita U.
- DOI
-
10.1055/s-0041-1736398
- URN
-
urn:nbn:de:101:1-2022031909080992048774
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
15.08.2025, 07:21 MESZ
Datenpartner
Dieses Objekt wird bereitgestellt von:
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Joshi, Anagha R.
- Kulkarni, Kiran
- Shah, Ankita U.
Ähnliche Objekte (12)
Leukoencephalopathy with cerebral calcifications and cysts: a case report
Adult-onset leukoencephalopathy, brain calcifications and cysts: a case report
Leukoencephalopathy with brain calcifications and cysts (Labrune syndrome) case report: diagnosis and management of a rare neurological disease
Flecked Calcifications in Scalp Tumors: Two Cases of Giant Ulcerated Trichilemmal Cysts
Bipolar disorder in megalencephalic leukoencephalopathy with subcortical cysts: a case report
Late radiation therapy brain abnormalities that mimic leukoencephalopathy with anterior temporal lobe cysts
Neurocysticercosis, familial cerebral cavernomas and intracranial calcifications: differential diagnosis for adequate management
KARS-related diseases: progressive leukoencephalopathy with brainstem and spinal cord calcifications as new phenotype and a review of literature
Evaluation of breast calcifications
Studien zur Expression von megalencephalic leukoencephalopathy with subcortical cysts 1 (MLC1/Mlc1) in humanen und murinen Geweben
Studien zur Expression von Megalencephalic leukoencephalopathy with subcortical cysts 1 (MLC1/Mlc1) in humanen und murinen Geweben
Reversible leukoencephalopathy with seizures: a case of severe high-altitude cerebral edema
Leukoencephalopathy with cerebral calcifications and cysts: a case report
Adult-onset leukoencephalopathy, brain calcifications and cysts: a case report
Leukoencephalopathy with brain calcifications and cysts (Labrune syndrome) case report: diagnosis and management of a rare neurological disease
Flecked Calcifications in Scalp Tumors: Two Cases of Giant Ulcerated Trichilemmal Cysts
Bipolar disorder in megalencephalic leukoencephalopathy with subcortical cysts: a case report
Late radiation therapy brain abnormalities that mimic leukoencephalopathy with anterior temporal lobe cysts
Neurocysticercosis, familial cerebral cavernomas and intracranial calcifications: differential diagnosis for adequate management
KARS-related diseases: progressive leukoencephalopathy with brainstem and spinal cord calcifications as new phenotype and a review of literature
Evaluation of breast calcifications
Studien zur Expression von megalencephalic leukoencephalopathy with subcortical cysts 1 (MLC1/Mlc1) in humanen und murinen Geweben
Studien zur Expression von Megalencephalic leukoencephalopathy with subcortical cysts 1 (MLC1/Mlc1) in humanen und murinen Geweben
Reversible leukoencephalopathy with seizures: a case of severe high-altitude cerebral edema
Leukoencephalopathy with cerebral calcifications and cysts: a case report
Adult-onset leukoencephalopathy, brain calcifications and cysts: a case report
Leukoencephalopathy with brain calcifications and cysts (Labrune syndrome) case report: diagnosis and management of a rare neurological disease
Flecked Calcifications in Scalp Tumors: Two Cases of Giant Ulcerated Trichilemmal Cysts
Bipolar disorder in megalencephalic leukoencephalopathy with subcortical cysts: a case report
Late radiation therapy brain abnormalities that mimic leukoencephalopathy with anterior temporal lobe cysts
Neurocysticercosis, familial cerebral cavernomas and intracranial calcifications: differential diagnosis for adequate management
KARS-related diseases: progressive leukoencephalopathy with brainstem and spinal cord calcifications as new phenotype and a review of literature
Evaluation of breast calcifications
Studien zur Expression von megalencephalic leukoencephalopathy with subcortical cysts 1 (MLC1/Mlc1) in humanen und murinen Geweben
Studien zur Expression von Megalencephalic leukoencephalopathy with subcortical cysts 1 (MLC1/Mlc1) in humanen und murinen Geweben