Enhanced Directed Evolution in Mammalian Cells Yields a Hyperefficient Pyrrolysyl tRNA for Noncanonical Amino Acid Mutagenesis
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Enhanced Directed Evolution in Mammalian Cells Yields a Hyperefficient Pyrrolysyl tRNA for Noncanonical Amino Acid Mutagenesis ; day:26 ; month:01 ; year:2024 ; extent:9
Angewandte Chemie ; (26.01.2024) (gesamt 9)
- Urheber
-
Jewel, Delilah
Kelemen, Rachel E.
Huang, Rachel L.
Zhu, Zeyu
Sundaresh, Bharathi
Malley, Kaitlin
Pham, Quan
Loynd, Conor
Huang, Zeyi
van Opijnen, Tim
Chatterjee, Abhishek
- DOI
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10.1002/ange.202316428
- URN
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urn:nbn:de:101:1-2024012714064083596185
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:21 MESZ
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Beteiligte
- Jewel, Delilah
- Kelemen, Rachel E.
- Huang, Rachel L.
- Zhu, Zeyu
- Sundaresh, Bharathi
- Malley, Kaitlin
- Pham, Quan
- Loynd, Conor
- Huang, Zeyi
- van Opijnen, Tim
- Chatterjee, Abhishek
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Enhanced Directed Evolution in Mammalian Cells Yields a Hyperefficient Pyrrolysyl tRNA for Noncanonical Amino Acid Mutagenesis
The Elongator subunit Elp3 is a non-canonical tRNA acetyltransferase
Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins
Co‐translational Installation of Posttranslational Modifications by Non‐canonical Amino Acid Mutagenesis
RNA mutagenesis yields highly diverse mRNA libraries for in vitroprotein evolution
Variations in the tRNA pool of mammalian cells upon differentiation and oxidative stress
Induction of proteasomal activity in mammalian cells by lifespan-extending tRNA synthetase inhibitors
Combinatorial InVitroFlow-assisted mutagenesis (CombIMut) yields a 41-fold improved CelA2 cellulase
Engineering of a mammalian VMAT2 for cryo-EM analysis results in non-canonical protein folding
A tRNA world
Non-Canonical Grammar!?
Automated orthogonal tRNA generation
Enhanced Directed Evolution in Mammalian Cells Yields a Hyperefficient Pyrrolysyl tRNA for Noncanonical Amino Acid Mutagenesis
The Elongator subunit Elp3 is a non-canonical tRNA acetyltransferase
Combinatorial mutagenesis of rapidly evolving residues yields super-restrictor antiviral proteins
Co‐translational Installation of Posttranslational Modifications by Non‐canonical Amino Acid Mutagenesis
RNA mutagenesis yields highly diverse mRNA libraries for in vitroprotein evolution
Variations in the tRNA pool of mammalian cells upon differentiation and oxidative stress
Induction of proteasomal activity in mammalian cells by lifespan-extending tRNA synthetase inhibitors
Combinatorial InVitroFlow-assisted mutagenesis (CombIMut) yields a 41-fold improved CelA2 cellulase
Engineering of a mammalian VMAT2 for cryo-EM analysis results in non-canonical protein folding
A tRNA world
Non-Canonical Grammar!?