Arbeitspapier

Preventative Cancer Treatments Through Optimizing Tissue Structure

The likelihood of cancer emergence is highly dependent on the underlying tissue structure. This article gives evolutionary explanations for why natural selection fails to select for tissue structures that would minimize the likelihood of cancer. In a second step, a mathematical framework is proposed, within which the risk of cancer emergence can be expressed and calculated dependent on a given tissue structure. This can be used to identify optimal structures and strategies for improvement. Lastly, the article explores both, ways to identify target areas for such intervention, as well as avenues towards developing treatment options.

Language
Englisch

Bibliographic citation
Series: Tinbergen Institute Discussion Paper ; No. TI 2020-012/II

Classification
Wirtschaft
Other Special Topics: General
Stochastic and Dynamic Games; Evolutionary Games; Repeated Games
Health: General
Subject
Evolution
Evolutionary Game Theory
Cancer

Event
Geistige Schöpfung
(who)
Graser, Christopher
Event
Veröffentlichung
(who)
Tinbergen Institute
(where)
Amsterdam and Rotterdam
(when)
2020

Handle
Last update
10.03.2025, 11:45 AM CET

Data provider

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Object type

  • Arbeitspapier

Associated

  • Graser, Christopher
  • Tinbergen Institute

Time of origin

  • 2020

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