Transition Metal‐Free Catalytic C−H Silylation of Terminal Alkynes with bis (Trimethylsilyl) acetylene Initiated by KHMDS
Abstract: Commercially available and inexpensive potassium bis (trimethylsilyl) amide (KHMDS) serves as an efficient transition metal‐free catalyst for the catalytic sp C−H silylation of several terminal alkynes including two pharmaceuticals. Overall, the presented system allows the synthesis of various attractive silylacetylenes under mild conditions, making this approach an environmentally benign and sustainable alternative to existing synthetic solutions.
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Erschienen in
-
Transition Metal‐Free Catalytic C−H Silylation of Terminal Alkynes with bis (Trimethylsilyl) acetylene Initiated by KHMDS ; day:19 ; month:07 ; year:2022 ; extent:1
ChemCatChem ; (19.07.2022) (gesamt 1)
- Urheber
-
Kuciński, Krzysztof
Hreczycho, Grzegorz
- DOI
-
10.1002/cctc.202200794
- URN
-
urn:nbn:de:101:1-2022072015352282476355
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
- 15.08.2025, 07:23 MESZ
Datenpartner
Dieses Objekt wird bereitgestellt von:
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Kuciński, Krzysztof
- Hreczycho, Grzegorz
Ähnliche Objekte (12)
Zwitterion‐Initiated Hydroboration of Alkynes and Styrene
Amine–borane complex-initiated SF5Cl radical addition on alkenes and alkynes
Metal‐Free and syn ‐Selective Hydrohalogenation of Alkynes through a Pseudo‐Intramolecular Process
Correction: Amine–borane complex-initiated SF5Cl radical addition on alkenes and alkynes
Nitric Acid Promoted Metal-Free Bromothiolation of Internal Alkynes with Hydrobromic Acid and Disulfides
Autonomous Visualization of Damage in Polymers by Metal‐Free Polymerizations of Microencapsulated Activated Alkynes
Advantages of Group 4 Metallocene Bis (trimethylsilyl) acetylene Complexes as Metallocene Sources Towards Other Synthetically used Systems
Latest News: Reactions of Group 4 Bis (trimethylsilyl) acetylene Metallocene Complexes and Applications of the Obtained Products
Heterosubstituierte Acetylene
Heterocyclische Acetylene
A general metal-free approach for the stereoselective synthesis of C-glycals from unactivated alkynes
Regio- and stereoselective access to highly substituted vinylphosphine oxides via metal-free electrophilic phosphonoiodination of alkynes
Zwitterion‐Initiated Hydroboration of Alkynes and Styrene
Amine–borane complex-initiated SF5Cl radical addition on alkenes and alkynes
Metal‐Free and syn ‐Selective Hydrohalogenation of Alkynes through a Pseudo‐Intramolecular Process
Correction: Amine–borane complex-initiated SF5Cl radical addition on alkenes and alkynes
Nitric Acid Promoted Metal-Free Bromothiolation of Internal Alkynes with Hydrobromic Acid and Disulfides
Autonomous Visualization of Damage in Polymers by Metal‐Free Polymerizations of Microencapsulated Activated Alkynes
Advantages of Group 4 Metallocene Bis (trimethylsilyl) acetylene Complexes as Metallocene Sources Towards Other Synthetically used Systems
Latest News: Reactions of Group 4 Bis (trimethylsilyl) acetylene Metallocene Complexes and Applications of the Obtained Products
Heterosubstituierte Acetylene
Heterocyclische Acetylene
A general metal-free approach for the stereoselective synthesis of C-glycals from unactivated alkynes
Regio- and stereoselective access to highly substituted vinylphosphine oxides via metal-free electrophilic phosphonoiodination of alkynes
Zwitterion‐Initiated Hydroboration of Alkynes and Styrene
Amine–borane complex-initiated SF5Cl radical addition on alkenes and alkynes
Metal‐Free and syn ‐Selective Hydrohalogenation of Alkynes through a Pseudo‐Intramolecular Process
Correction: Amine–borane complex-initiated SF5Cl radical addition on alkenes and alkynes
Nitric Acid Promoted Metal-Free Bromothiolation of Internal Alkynes with Hydrobromic Acid and Disulfides
Autonomous Visualization of Damage in Polymers by Metal‐Free Polymerizations of Microencapsulated Activated Alkynes
Advantages of Group 4 Metallocene Bis (trimethylsilyl) acetylene Complexes as Metallocene Sources Towards Other Synthetically used Systems
Latest News: Reactions of Group 4 Bis (trimethylsilyl) acetylene Metallocene Complexes and Applications of the Obtained Products
Heterosubstituierte Acetylene
Heterocyclische Acetylene
A general metal-free approach for the stereoselective synthesis of C-glycals from unactivated alkynes