Hyperreactio luteinalis in association with multiple foetal malformations – a consequence of supra-physiological HCG?
Abstract: Aim: Hyperreactio luteinalis (HL) is characterised by ovarian cystic enlargement that is associated with high levels of human chorionic gonadotropin (hCG). Here the possible effects of abnormally high hCG levels on foetal development are demonstrated. Method: We report a 28-year-old patient who was referred for evaluation of bilateral maternal ovarian enlargement in the second trimester. Abnormally elevated hCG (887,514 IU/L) was found with ultrasound examination identifying various foetal malformations. The karyotype was normal. Spontaneous abortion occurred at 20 weeks. Autopsy showed testicular hypertrophy with marked Leydig cell hyperplasia. The HL resolved with normalisation of the hCG levels following delivery. Conclusion: HL is a rare finding in normal pregnancies; the potential effects of abnormally elevated hCG on the foetus are discussed.
- Standort
-
Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
-
Online-Ressource
- Sprache
-
Englisch
- Erschienen in
-
Hyperreactio luteinalis in association with multiple foetal malformations – a consequence of supra-physiological HCG? ; volume:3 ; number:1 ; year:2014 ; pages:5-9 ; extent:5
Case reports in perinatal medicine ; 3, Heft 1 (2014), 5-9 (gesamt 5)
- Urheber
-
Faden, Majed
Salehi, Amir H.
Simon, Jeannine
Chen, Moy Fong
Omeroglu, Atilla
Brown, Richard
- DOI
-
10.1515/crpm-2013-0030
- URN
-
urn:nbn:de:101:1-2411121457031.574210686510
- Rechteinformation
-
Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
-
15.08.2025, 07:27 MESZ
Datenpartner
Deutsche Nationalbibliothek. Bei Fragen zum Objekt wenden Sie sich bitte an den Datenpartner.
Beteiligte
- Faden, Majed
- Salehi, Amir H.
- Simon, Jeannine
- Chen, Moy Fong
- Omeroglu, Atilla
- Brown, Richard
Ähnliche Objekte (12)
Diagnostic assessment of foetal brain malformations with intra-uterine MRI versus perinatal post-mortem MRI
Foetal attraction
Mutations in tubulin genes are frequent causes of various foetal malformations of cortical development including microlissencephaly
Das Mamma-Carcinom als Produktionsstätte von AFP, HCG und β-HCG [Beta-HCG]
Diagnosis of single umbilical artery and risk of foetal congenital malformations by prenatal ultrasound: a retrospective study
Die diagnostische Bedeutung der β-HCG- [Beta-HCG-] und HCG-Bestimmung in der gynäkologischen Onkologie
The Consequence of the Consequence Argument
Foetal oestrogens and autism
Vergleichende Wertung kommerzieller HCG-Radioimmunoassays und Anwendung von HCG als Tumormarker
No consequence
Anorectal malformations
Zur ACTH-abhängigen β-HCG-Stimulation [beta-HCG-Stimulation] in der Terminplazenta
Diagnostic assessment of foetal brain malformations with intra-uterine MRI versus perinatal post-mortem MRI
Foetal attraction
Mutations in tubulin genes are frequent causes of various foetal malformations of cortical development including microlissencephaly
Das Mamma-Carcinom als Produktionsstätte von AFP, HCG und β-HCG [Beta-HCG]
Diagnosis of single umbilical artery and risk of foetal congenital malformations by prenatal ultrasound: a retrospective study
Die diagnostische Bedeutung der β-HCG- [Beta-HCG-] und HCG-Bestimmung in der gynäkologischen Onkologie
The Consequence of the Consequence Argument
Foetal oestrogens and autism
Vergleichende Wertung kommerzieller HCG-Radioimmunoassays und Anwendung von HCG als Tumormarker
No consequence
Anorectal malformations
Zur ACTH-abhängigen β-HCG-Stimulation [beta-HCG-Stimulation] in der Terminplazenta
Diagnostic assessment of foetal brain malformations with intra-uterine MRI versus perinatal post-mortem MRI
Foetal attraction
Mutations in tubulin genes are frequent causes of various foetal malformations of cortical development including microlissencephaly
Das Mamma-Carcinom als Produktionsstätte von AFP, HCG und β-HCG [Beta-HCG]
Diagnosis of single umbilical artery and risk of foetal congenital malformations by prenatal ultrasound: a retrospective study
Die diagnostische Bedeutung der β-HCG- [Beta-HCG-] und HCG-Bestimmung in der gynäkologischen Onkologie
The Consequence of the Consequence Argument
Foetal oestrogens and autism
Vergleichende Wertung kommerzieller HCG-Radioimmunoassays und Anwendung von HCG als Tumormarker
No consequence
Anorectal malformations