Spot‐on SERS Detection of Biomolecules with Laser‐Patterned Dot Arrays of Assembled Silver Nanowires
Abstract: Unique characteristics of SERS including the possibility to reveal the compositional and structural content of trace amounts of biological samples without any pre‐treatment, depict this technique as a promising label‐free alternative to standard analytical methods. Despite significant advancements, current SERS substrates for biomolecule detection suffer from a number of issues still impeding their routine usage and commercial exploitation, including complex and expensive fabrication procedures and scarce standardization perspectives. Herein a combined bottom up/top down scheme based on flow‐through method plus laser patterning is proposed to prepare dot arrays of silver nanowires on a hydrophobic substrate for catching the analyte content from a minute amount of liquid sample and its rapid SERS inspection. As a consequence, a simple spot‐on analysis specifically adapted for reliable identification and characterization of molecules of biomedical interest is made possible. Our attempt may represent a concrete chance for progressing SERS toward widespread commercially viable sensing applications including diagnostics at the point‐of‐need settings and on‐site analyses.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Spot‐on SERS Detection of Biomolecules with Laser‐Patterned Dot Arrays of Assembled Silver Nanowires ; volume:5 ; number:8 ; year:2019 ; pages:1036-1043 ; extent:8
ChemNanoMat ; 5, Heft 8 (2019), 1036-1043 (gesamt 8)
- Creator
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Banchelli, Martina
Amicucci, Chiara
Ruggiero, Emmanuel
D’Andrea, Cristiano
Cottat, Maximilien
Ciofini, Daniele
Osticioli, Iacopo
Ghini, Giacomo
Siano, Salvatore
Pini, Roberto
de Angelis, Marella
Matteini, Paolo
- DOI
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10.1002/cnma.201900035
- URN
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urn:nbn:de:101:1-2022080612175082921886
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:34 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Banchelli, Martina
- Amicucci, Chiara
- Ruggiero, Emmanuel
- D’Andrea, Cristiano
- Cottat, Maximilien
- Ciofini, Daniele
- Osticioli, Iacopo
- Ghini, Giacomo
- Siano, Salvatore
- Pini, Roberto
- de Angelis, Marella
- Matteini, Paolo
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Electrostatically self-assembled nanoparticles based on biomolecules
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