The use of negative-pressure wound therapy over a cultured epithelial autograft for full-thickness wounds secondary to purpura fulminans in an infant
Abstract: Purpura fulminans is a serious condition that can result in severe morbidity in the pediatric population. Although autologous skin grafts remain the gold standard for the coverage of partial- to full-thickness wounds, they have several limitations in pediatric patients, including the lack of planar donor sites, the risk of hemodynamic instability, and the limited graft thickness. In Singapore, an in-house skin culture laboratory has been available since 2005 for the use of cultured epithelial autografts (CEAs), especially in burn wounds. However, due to the fragility of CEAs, negative-pressure wound therapy (NPWT) dressings have been rarely used with CEAs. With several modifications, we report a successful case of NPWT applied over a CEA in an infant who sustained 30% total body surface area full-thickness wounds over the anterior abdomen, flank, and upper thigh secondary to purpura fulminans. We also describe the advantages of using NPWT dressing over a CEA, particularly in pediatric patients.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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The use of negative-pressure wound therapy over a cultured epithelial autograft for full-thickness wounds secondary to purpura fulminans in an infant ; volume:48 ; number:03 ; year:2021 ; pages:338-343
Archives of Plastic Surgery ; 48, Heft 03 (2021), 338-343
- Beteiligte Personen und Organisationen
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Goh, Benjamin Kah Liang
Chua, Alvin Wen Choong
Chew, Khong Yik
Kang, Gavin Chun-Wui
Chiang, Li-Wei
Tan, Bien-Keem
Ramachandran, Savitha
- DOI
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10.5999/aps.2020.01032
- URN
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urn:nbn:de:101:1-2022050512303247987934
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:20 MESZ
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Beteiligte
- Goh, Benjamin Kah Liang
- Chua, Alvin Wen Choong
- Chew, Khong Yik
- Kang, Gavin Chun-Wui
- Chiang, Li-Wei
- Tan, Bien-Keem
- Ramachandran, Savitha
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