Pleural fluid biochemical analysis: the past, present and future
Abstract: Identifying the cause of pleural effusion is challenging for pulmonologists. Imaging, biopsy, microbiology and biochemical analyses are routinely used for diagnosing pleural effusion. Among these diagnostic tools, biochemical analyses are promising because they have the advantages of low cost, minimal invasiveness, observer independence and short turn-around time. Here, we reviewed the past, present and future of pleural fluid biochemical analysis. We reviewed the history of Light’s criteria and its modifications and the current status of biomarkers for heart failure, malignant pleural effusion, tuberculosis pleural effusion and parapneumonic pleural effusion. In addition, we anticipate the future of pleural fluid biochemical analysis, including the utility of machine learning, molecular diagnosis and high-throughput technologies. Clinical Chemistry and Laboratory Medicine (CCLM) should address the topic of pleural fluid biochemical analysis in the future to promote specific knowledge in the laboratory professional community.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Pleural fluid biochemical analysis: the past, present and future ; volume:61 ; number:5 ; year:2023 ; pages:921-934 ; extent:014
Clinical chemistry and laboratory medicine ; 61, Heft 5 (2023), 921-934 (gesamt 014)
- Creator
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Zheng, Wen-Qi
Hu, Zhi-De
- DOI
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10.1515/cclm-2022-0844
- URN
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urn:nbn:de:101:1-2023033114203323241400
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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14.08.2025, 10:48 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Zheng, Wen-Qi
- Hu, Zhi-De
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