Enantioselective Generation of Adjacent Stereocenters in a Copper‐Catalyzed Three‐Component Coupling of Imines, Allenes, and Diboranes
Abstract: A highly enantio‐ and diastereoselective copper‐catalyzed three‐component coupling affords the first general synthesis of homoallylic amines bearing adjacent stereocenters from achiral starting materials. The method utilizes a commercially available NHC ligand and copper source, operates at ambient temperature, couples readily available simple imines, allenes, and diboranes, and yields high‐value homoallylic amines that exhibit versatile amino, alkenyl, and boryl units.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Enantioselective Generation of Adjacent Stereocenters in a Copper‐Catalyzed Three‐Component Coupling of Imines, Allenes, and Diboranes ; volume:128 ; number:39 ; year:2016 ; pages:12091-12095 ; extent:5
Angewandte Chemie ; 128, Heft 39 (2016), 12091-12095 (gesamt 5)
- Urheber
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Yeung, Kay
Ruscoe, Rebecca E.
Rae, James
Pulis, Alexander P.
Procter, David J.
- DOI
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10.1002/ange.201606710
- URN
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urn:nbn:de:101:1-2022101008233938781882
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
- 15.08.2025, 07:27 MESZ
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Beteiligte
- Yeung, Kay
- Ruscoe, Rebecca E.
- Rae, James
- Pulis, Alexander P.
- Procter, David J.
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