Copper‐Catalyzed Borylative Cross‐Coupling of Allenes and Imines: Selective Three‐Component Assembly of Branched Homoallyl Amines
Abstract: A copper‐catalyzed three‐component coupling of allenes, bis (pinacolato) diboron, and imines allows regio‐, chemo‐, and diastereoselective assembly of branched α,β‐substituted‐γ‐boryl homoallylic amines, that is, products bearing versatile amino, alkenyl, and borane functionality. Alternatively, convenient oxidative workup allows access to α‐substituted‐β‐amino ketones. A computational study has been used to probe the stereochemical course of the cross‐coupling.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Copper‐Catalyzed Borylative Cross‐Coupling of Allenes and Imines: Selective Three‐Component Assembly of Branched Homoallyl Amines ; volume:55 ; number:3 ; year:2016 ; pages:1102-1107 ; extent:6
Angewandte Chemie / International edition. International edition ; 55, Heft 3 (2016), 1102-1107 (gesamt 6)
- Urheber
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Rae, James
Yeung, Kay
McDouall, Joseph J. W.
Procter, David J.
- DOI
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10.1002/anie.201508959
- URN
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urn:nbn:de:101:1-2022110108163754053032
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:31 MESZ
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Beteiligte
- Rae, James
- Yeung, Kay
- McDouall, Joseph J. W.
- Procter, David J.
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