Synthesis and application of nanometer hydroxyapatite in biomedicine
Abstract: Nano-hydroxyapatite (nano-HA) has been widely studied as a promising biomaterial because of its potential mechanical and biological properties. In this article, different synthesis methods for nano-HA were summarized. Key factors for the synthesis of nano-HA, including reactant concentration, effects of temperature, PH, additives, aging time, and sintering, were separately investigated. The biological performances of the nano-HA depend strongly on its structures, morphology, and crystallite sizes. Nano-HA with different morphologies may cause different biological effects, such as protein adsorption, cell viability and proliferation, angiogenesis, and vascularization. Recent research progress with respect to the biological functions of the nano-HA in some specific biological applications are summarized and the future development of nano-sized hydroxyapatite is prospected.
- Standort
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Deutsche Nationalbibliothek Frankfurt am Main
- Umfang
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Online-Ressource
- Sprache
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Englisch
- Erschienen in
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Synthesis and application of nanometer hydroxyapatite in biomedicine ; volume:11 ; number:1 ; year:2022 ; pages:2154-2168 ; extent:15
Nanotechnology reviews ; 11, Heft 1 (2022), 2154-2168 (gesamt 15)
- Urheber
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Gui, Xingyu
Peng, Wei
Xu, Xiujuan
Su, Zixuan
Liu, Gang
Zhou, Zhigang
Liu, Ming
Li, Zhao
Song, Geyang
Zhou, Changchun
Kong, Qingquan
- DOI
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10.1515/ntrev-2022-0127
- URN
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urn:nbn:de:101:1-2022071514413630989033
- Rechteinformation
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Letzte Aktualisierung
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15.08.2025, 07:28 MESZ
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Beteiligte
- Gui, Xingyu
- Peng, Wei
- Xu, Xiujuan
- Su, Zixuan
- Liu, Gang
- Zhou, Zhigang
- Liu, Ming
- Li, Zhao
- Song, Geyang
- Zhou, Changchun
- Kong, Qingquan
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