Recent Advances in Host–Guest Self‐Assembled Cyclodextrin Carriers: Implications for Responsive Drug Delivery and Biomedical Engineering
Abstract: This Review is an overview of the unique characteristics of cyclodextrin in forming an inclusion complex via host–guest noncovalent interactions. The modification of cyclodextrin advances its application as a pharmaceutical solubilizer, fabrication of functional molecular machines such as polyrotaxane, polypseudorotaxane, and polycatenanes and grafting of cyclodextrin with different linear, branched chain polymers. The different stimuli‐based supramolecular assemblies involving cyclodextrin as a key mediator with linked triggering responses on payload release is highlighted. In addition, the applications of cyclodextrin in diagnostic imaging and medical devices is briefly demonstrated. Cyclodextrin is a relatively low cost, biocompatible, biodegradable, and highly explored material with low toxicity for drug formulation, drug delivery, and wide varieties of other biomedical applications such as those in medical devices fabrication, biosensor, tissue engineering, and bio‐imaging. The toxicological profile of cyclodextrin is well established and safe for human consumption in food and medicine.
- Location
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Deutsche Nationalbibliothek Frankfurt am Main
- Extent
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Online-Ressource
- Language
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Englisch
- Bibliographic citation
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Recent Advances in Host–Guest Self‐Assembled Cyclodextrin Carriers: Implications for Responsive Drug Delivery and Biomedical Engineering ; volume:30 ; number:44 ; year:2020 ; extent:27
Advanced functional materials ; 30, Heft 44 (2020) (gesamt 27)
- Creator
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Wankar, Jitendra
Kotla, Niranjan G.
Gera, Sonia
Rasala, Swetha
Pandit, Abhay
Rochev, Yury A.
- DOI
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10.1002/adfm.201909049
- URN
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urn:nbn:de:101:1-2022060907563102879117
- Rights
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Open Access; Der Zugriff auf das Objekt ist unbeschränkt möglich.
- Last update
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15.08.2025, 7:33 AM CEST
Data provider
Deutsche Nationalbibliothek. If you have any questions about the object, please contact the data provider.
Associated
- Wankar, Jitendra
- Kotla, Niranjan G.
- Gera, Sonia
- Rasala, Swetha
- Pandit, Abhay
- Rochev, Yury A.
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Fluorescence quenching in β-cyclodextrin vesicles: membrane confinement and host-guest interactions
Novel Macromolecular Architectures via a Combination of Cyclodextrin Host/Guest Complexation and RAFT Polymerizatio
Formation of Supramolecular Gels from Host–Guest Interactions between PEGylated Chitosan and α ‐Cyclodextrin
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Self-assembled organic–inorganic magnetic hybrid adsorbent ferrite based on cyclodextrin nanoparticles
Cyclodextrin-induced host–guest effects of classically prepared poly(NIPAM) bearing azo-dye end groups
Host‐Guest Stimuli‐Responsive Click Chemistry
Bio-Mimetic Supramolecular Host–Guest Interactions
Metallacycles Capabilities in Host–Guest Chemistry
Spatial arrangements of cyclodextrin host–guest complexes in solution studied by 13C NMR and molecular modelling
A self-assembled cyclodextrin nanocarrier for photoreactive squaraine
Supramolecular polymer assembly in aqueous solution arising from cyclodextrin host–guest complexation
Fluorescence quenching in β-cyclodextrin vesicles: membrane confinement and host-guest interactions
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Formation of Supramolecular Gels from Host–Guest Interactions between PEGylated Chitosan and α ‐Cyclodextrin
Photoresponsive Double Cross‐Linked Supramolecular Hydrogels Based on Α‐cyclodextrin/Azobenzene Host–Guest Complex
Self-assembled organic–inorganic magnetic hybrid adsorbent ferrite based on cyclodextrin nanoparticles
Cyclodextrin-induced host–guest effects of classically prepared poly(NIPAM) bearing azo-dye end groups
Host‐Guest Stimuli‐Responsive Click Chemistry
Bio-Mimetic Supramolecular Host–Guest Interactions
Metallacycles Capabilities in Host–Guest Chemistry